Chimpanzee-origin adenovirus vectors as vaccine carriers

Vaccines based on replication-defective adenoviral vectors are being developed for infectious agents and tumor-associated antigens. Early work focused on vaccines derived from a common human serotype of adenovirus, that is, adenovirus of the serotype 5 (AdHu5). Neutralizing antibodies against AdHu5...

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Veröffentlicht in:	Gene therapy 2006-03, Vol.13 (5), p.421-429
Hauptverfasser:	Tatsis, N, Tesema, L, Robinson, E R, Giles-Davis, W, McCoy, K, Gao, G P, Wilson, J M, Ertl, H C J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Adenoviridae Infections - immunology Adenovirus Adenoviruses Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Antigen (tumor-associated) Antigens - immunology Applied cell therapy and gene therapy Biological and medical sciences Biomedical and Life Sciences Biomedicine Bioreactors Biotechnology Care and treatment CD8-Positive T-Lymphocytes - immunology Cell Biology Cell Line DNA vaccines Expression vectors Female Fundamental and applied biological sciences. Psychology Gene Expression Gene Therapy Genetic aspects Genetic Engineering Genetic Vectors - administration & dosage Genetic Vectors - genetics Health aspects Health. Pharmaceutical industry HIV infection Human Genetics Immunoblotting Industrial applications and implications. Economical aspects Medical sciences Mice Mice, Inbred BALB C Mice, Inbred C57BL Monkeys & apes Nanotechnology original-article Pan troglodytes Pan troglodytes - virology Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transgenes Tumors Vaccines Viral Vaccines - administration & dosage Viral Vaccines - genetics
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