Characterization of Oligomers during α-Synuclein Aggregation Using Intrinsic Tryptophan Fluorescence

The aggregation of the presynaptic protein α-synuclein is associated with Parkinson's disease (PD). The details of the mechanism of aggregation, as well as the cytotoxic species, are currently not well understood. α-Synuclein has four tyrosine and no tryptophan residues. We introduced a tyrosin...

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