A block in the road to fertility: autoantibodies to heat-shock protein 90-β in human ovarian autoimmunity

Objective To report autoantibodies to human heat-shock protein 90-β (HSP90β) in sera of women with infertility. Design Prospective, controlled observations. Setting Major urban infertility referral center and research institution. Patient(s) Fifty women with premature ovarian failure, 65 infertile w...

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Veröffentlicht in:	Fertility and sterility 2009-10, Vol.92 (4), p.1395-1409
Hauptverfasser:	Pires, Eusebio S., Ph.D, Khole, Vrinda V., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals autoantibodies Autoantibodies - blood Autoantibodies - isolation & purification Autoantibodies - metabolism Autoimmune Diseases - complications Autoimmune Diseases - immunology Autoimmunity - immunology Autoimmunity - physiology Biological and medical sciences Case-Control Studies Female Fertility - immunology Gynecology. Andrology. Obstetrics heat-shock protein 90 HSP90 Heat-Shock Proteins - immunology Humans immunodominant antigens Infertility, Female - etiology Infertility, Female - immunology Internal Medicine IVF-ET Medical sciences Mice Obstetrics and Gynecology Ovarian autoimmunity Ovary - immunology Ovary - metabolism POF Primary Ovarian Insufficiency - blood Primary Ovarian Insufficiency - complications Primary Ovarian Insufficiency - immunology Rabbits Rats Rats, Sprague-Dawley Swine
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