Prevalence of COPD in Spain: impact of undiagnosed COPD on quality of life and daily life activities

Aims:This study aimed to determine the prevalence of chronic obstructive pulmonary disease (COPD) in Spain and identify the level of undiagnosed disease and its impact on health-related quality of life (HRQL) and activities of daily living (ADL).Methods:A population-based sample of 4274 adults aged...

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Veröffentlicht in:Thorax 2009-10, Vol.64 (10), p.863-868
Hauptverfasser: Miravitlles, M, Soriano, J B, García-Río, F, Muñoz, L, Duran-Tauleria, E, Sanchez, G, Sobradillo, V, Ancochea, J
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container_end_page 868
container_issue 10
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container_title Thorax
container_volume 64
creator Miravitlles, M
Soriano, J B
García-Río, F
Muñoz, L
Duran-Tauleria, E
Sanchez, G
Sobradillo, V
Ancochea, J
description Aims:This study aimed to determine the prevalence of chronic obstructive pulmonary disease (COPD) in Spain and identify the level of undiagnosed disease and its impact on health-related quality of life (HRQL) and activities of daily living (ADL).Methods:A population-based sample of 4274 adults aged 40–80 years was surveyed. They were invited to answer a questionnaire and undergo prebrochodilator and postbronchodilator spirometry. COPD was defined as a postbronchodilator FEV1/FVC (forced expiratory volume in 1 s/forced vital capacity) ratio of
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They were invited to answer a questionnaire and undergo prebrochodilator and postbronchodilator spirometry. COPD was defined as a postbronchodilator FEV1/FVC (forced expiratory volume in 1 s/forced vital capacity) ratio of &lt;0.70.Results:For 3802 participants with good-quality postbronchodilator spirometry, the overall prevalence of COPD was 10.2% (95% CI 9.2% to 11.1%) and was higher in men (15.1%) than in women (5.6%). The prevalence of COPD stage II or higher was 4.4% (95%CI; 3.8%–5.1%). The prevalence of COPD increased with age and with cigarette smoking and was higher in those with a low educational level. A previous diagnosis of COPD was reported by only 27% of those with COPD. Diagnosed patients had more severe disease, higher cumulative tobacco consumption and more severely impaired HRQL compared with undiagnosed subjects. However, even patients with undiagnosed COPD stage I+ already showed impairment in HRQL and in some aspects of ADL compared with participants without COPD.Conclusions:The prevalence of COPD in individuals between 40 and 80 years of age in Spain is 10.2% and increases with age, tobacco consumption and lower educational levels. The rate of diagnosised COPD is very high and undiagnosed individuals with COPD already have a significant impairment in HRQL and ADL.</description><identifier>ISSN: 0040-6376</identifier><identifier>EISSN: 1468-3296</identifier><identifier>DOI: 10.1136/thx.2009.115725</identifier><identifier>PMID: 19553233</identifier><identifier>CODEN: THORA7</identifier><language>eng</language><publisher>London: BMJ Publishing Group</publisher><subject>Activities of Daily Living ; Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Cardiology. Vascular system ; Chronic obstructive pulmonary disease ; Chronic obstructive pulmonary disease, asthma ; Cost of Illness ; Cross-Sectional Studies ; Female ; Humans ; Male ; Medical sciences ; Middle Aged ; Pneumology ; Population ; Prevalence ; Pulmonary Disease, Chronic Obstructive - epidemiology ; Pulmonary Disease, Chronic Obstructive - psychology ; Quality of Life ; Questionnaires ; Risk Factors ; Spain - epidemiology ; Spirometry</subject><ispartof>Thorax, 2009-10, Vol.64 (10), p.863-868</ispartof><rights>BMJ Publishing Group Ltd and British Thoracic Society. All rights reserved.</rights><rights>2009 INIST-CNRS</rights><rights>Copyright: 2009 BMJ Publishing Group Ltd and British Thoracic Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b495t-2a8bdb898ae2db0169d45fb6ad8abab371682be5deba9590b8def1884cda65b43</citedby><cites>FETCH-LOGICAL-b495t-2a8bdb898ae2db0169d45fb6ad8abab371682be5deba9590b8def1884cda65b43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://thorax.bmj.com/content/64/10/863.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttps://thorax.bmj.com/content/64/10/863.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,776,780,3183,23550,27901,27902,77569,77600</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=21959192$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19553233$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Miravitlles, M</creatorcontrib><creatorcontrib>Soriano, J B</creatorcontrib><creatorcontrib>García-Río, F</creatorcontrib><creatorcontrib>Muñoz, L</creatorcontrib><creatorcontrib>Duran-Tauleria, E</creatorcontrib><creatorcontrib>Sanchez, G</creatorcontrib><creatorcontrib>Sobradillo, V</creatorcontrib><creatorcontrib>Ancochea, J</creatorcontrib><title>Prevalence of COPD in Spain: impact of undiagnosed COPD on quality of life and daily life activities</title><title>Thorax</title><addtitle>Thorax</addtitle><description>Aims:This study aimed to determine the prevalence of chronic obstructive pulmonary disease (COPD) in Spain and identify the level of undiagnosed disease and its impact on health-related quality of life (HRQL) and activities of daily living (ADL).Methods:A population-based sample of 4274 adults aged 40–80 years was surveyed. They were invited to answer a questionnaire and undergo prebrochodilator and postbronchodilator spirometry. COPD was defined as a postbronchodilator FEV1/FVC (forced expiratory volume in 1 s/forced vital capacity) ratio of &lt;0.70.Results:For 3802 participants with good-quality postbronchodilator spirometry, the overall prevalence of COPD was 10.2% (95% CI 9.2% to 11.1%) and was higher in men (15.1%) than in women (5.6%). The prevalence of COPD stage II or higher was 4.4% (95%CI; 3.8%–5.1%). The prevalence of COPD increased with age and with cigarette smoking and was higher in those with a low educational level. A previous diagnosis of COPD was reported by only 27% of those with COPD. Diagnosed patients had more severe disease, higher cumulative tobacco consumption and more severely impaired HRQL compared with undiagnosed subjects. However, even patients with undiagnosed COPD stage I+ already showed impairment in HRQL and in some aspects of ADL compared with participants without COPD.Conclusions:The prevalence of COPD in individuals between 40 and 80 years of age in Spain is 10.2% and increases with age, tobacco consumption and lower educational levels. The rate of diagnosised COPD is very high and undiagnosed individuals with COPD already have a significant impairment in HRQL and ADL.</description><subject>Activities of Daily Living</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Chronic obstructive pulmonary disease, asthma</subject><subject>Cost of Illness</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pneumology</subject><subject>Population</subject><subject>Prevalence</subject><subject>Pulmonary Disease, Chronic Obstructive - epidemiology</subject><subject>Pulmonary Disease, Chronic Obstructive - psychology</subject><subject>Quality of Life</subject><subject>Questionnaires</subject><subject>Risk Factors</subject><subject>Spain - epidemiology</subject><subject>Spirometry</subject><issn>0040-6376</issn><issn>1468-3296</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqF0N9L3TAUB_AgG3p1Pvs2CmM-CNX8aNLEN7n-2EBQUJ_DSZNuubTptWll979fSosDXwaBcDifnBO-CJ0QfE4IExfD7z_nFGOVKl5SvodWpBAyZ1SJT2iFcYFzwUpxgA5j3GCMJSHlPjoginNGGVsh-9i7N2hcqFzW1dn64fE68yF72oIPl5lvt1ANU2MM1sOv0EVnZ9SF7HWExg-7qd342mUQbGbBN7ulrAb_5gfv4hf0uYYmuuPlPkIvtzfP6x_5_cPdz_XVfW4KxYecgjTWSCXBUWswEcoWvDYCrAQDhpVESGoct86A4gobaV1NpCwqC4Kbgh2h03nutu9eRxcH3fpYuaaB4LoxalGKksiCJfjtA9x0Yx_S3zQpZTqCljSpi1lVfRdj72q97X0L_U4TrKf4dYpfT_HrOf704usydzSts__8kncC3xcAsYKm7iFUPr47mqAialp9NjvTbv679S9YPJo1</recordid><startdate>20091001</startdate><enddate>20091001</enddate><creator>Miravitlles, M</creator><creator>Soriano, J B</creator><creator>García-Río, F</creator><creator>Muñoz, L</creator><creator>Duran-Tauleria, E</creator><creator>Sanchez, G</creator><creator>Sobradillo, V</creator><creator>Ancochea, J</creator><general>BMJ Publishing Group</general><general>BMJ Publishing Group LTD</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20091001</creationdate><title>Prevalence of COPD in Spain: impact of undiagnosed COPD on quality of life and daily life activities</title><author>Miravitlles, M ; Soriano, J B ; García-Río, F ; Muñoz, L ; Duran-Tauleria, E ; Sanchez, G ; Sobradillo, V ; Ancochea, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b495t-2a8bdb898ae2db0169d45fb6ad8abab371682be5deba9590b8def1884cda65b43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Activities of Daily Living</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Chronic obstructive pulmonary disease, asthma</topic><topic>Cost of Illness</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pneumology</topic><topic>Population</topic><topic>Prevalence</topic><topic>Pulmonary Disease, Chronic Obstructive - epidemiology</topic><topic>Pulmonary Disease, Chronic Obstructive - psychology</topic><topic>Quality of Life</topic><topic>Questionnaires</topic><topic>Risk Factors</topic><topic>Spain - epidemiology</topic><topic>Spirometry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Miravitlles, M</creatorcontrib><creatorcontrib>Soriano, J B</creatorcontrib><creatorcontrib>García-Río, F</creatorcontrib><creatorcontrib>Muñoz, L</creatorcontrib><creatorcontrib>Duran-Tauleria, E</creatorcontrib><creatorcontrib>Sanchez, G</creatorcontrib><creatorcontrib>Sobradillo, V</creatorcontrib><creatorcontrib>Ancochea, J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Thorax</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Miravitlles, M</au><au>Soriano, J B</au><au>García-Río, F</au><au>Muñoz, L</au><au>Duran-Tauleria, E</au><au>Sanchez, G</au><au>Sobradillo, V</au><au>Ancochea, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of COPD in Spain: impact of undiagnosed COPD on quality of life and daily life activities</atitle><jtitle>Thorax</jtitle><addtitle>Thorax</addtitle><date>2009-10-01</date><risdate>2009</risdate><volume>64</volume><issue>10</issue><spage>863</spage><epage>868</epage><pages>863-868</pages><issn>0040-6376</issn><eissn>1468-3296</eissn><coden>THORA7</coden><abstract>Aims:This study aimed to determine the prevalence of chronic obstructive pulmonary disease (COPD) in Spain and identify the level of undiagnosed disease and its impact on health-related quality of life (HRQL) and activities of daily living (ADL).Methods:A population-based sample of 4274 adults aged 40–80 years was surveyed. They were invited to answer a questionnaire and undergo prebrochodilator and postbronchodilator spirometry. COPD was defined as a postbronchodilator FEV1/FVC (forced expiratory volume in 1 s/forced vital capacity) ratio of &lt;0.70.Results:For 3802 participants with good-quality postbronchodilator spirometry, the overall prevalence of COPD was 10.2% (95% CI 9.2% to 11.1%) and was higher in men (15.1%) than in women (5.6%). The prevalence of COPD stage II or higher was 4.4% (95%CI; 3.8%–5.1%). The prevalence of COPD increased with age and with cigarette smoking and was higher in those with a low educational level. A previous diagnosis of COPD was reported by only 27% of those with COPD. Diagnosed patients had more severe disease, higher cumulative tobacco consumption and more severely impaired HRQL compared with undiagnosed subjects. However, even patients with undiagnosed COPD stage I+ already showed impairment in HRQL and in some aspects of ADL compared with participants without COPD.Conclusions:The prevalence of COPD in individuals between 40 and 80 years of age in Spain is 10.2% and increases with age, tobacco consumption and lower educational levels. The rate of diagnosised COPD is very high and undiagnosed individuals with COPD already have a significant impairment in HRQL and ADL.</abstract><cop>London</cop><pub>BMJ Publishing Group</pub><pmid>19553233</pmid><doi>10.1136/thx.2009.115725</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
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subjects Activities of Daily Living
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Cardiology. Vascular system
Chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease, asthma
Cost of Illness
Cross-Sectional Studies
Female
Humans
Male
Medical sciences
Middle Aged
Pneumology
Population
Prevalence
Pulmonary Disease, Chronic Obstructive - epidemiology
Pulmonary Disease, Chronic Obstructive - psychology
Quality of Life
Questionnaires
Risk Factors
Spain - epidemiology
Spirometry
title Prevalence of COPD in Spain: impact of undiagnosed COPD on quality of life and daily life activities
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