Development of antibodies against the putative proteinase maturation protein A in relation to pneumococcal carriage and otitis media

Abstract The putative pneumococcal proteinase maturation protein A is a potential pneumococcal vaccine candidate. We examined serum antipneumococcal proteinase maturation protein A antibodies at 6, 12, 18 and 24 months of age, and showed that the age-related development of antipneumococcal proteinas...

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Veröffentlicht in:	FEMS immunology and medical microbiology 2006-03, Vol.46 (2), p.166-168
Hauptverfasser:	Bogaert, Debby, Holmlund, Emma, Lahdenkari, Mika, De Groot, Ronald, Kilpi, Terhi, Hermans, Peter W. M., Kayhty, Helena
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease acute otitis media Adult Age Antibodies Antibodies, Bacterial - blood Bacterial Proteins - immunology Carrier State - immunology Carrier State - microbiology Child, Preschool Confidence intervals Ear diseases Female Humans Immunoglobulins Infant Maturation Otitis media Otitis Media - immunology Otitis Media - microbiology Pneumococcal Infections - immunology Pneumococcal Infections - microbiology Pneumococcal Vaccines PpmA Protein A Proteinase Proteins Serine Endopeptidases - immunology Streptococcus infections Streptococcus pneumoniae Streptococcus pneumoniae - immunology Vaccines
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