Antibacterial and wound healing properties of methanolic extracts of some Nigerian medicinal plants
This study was conducted to evaluate methanolic extracts of Ageratum conyzoides, Anthocleista djalonensis, Napoleona imperialis, Ocimum gratissimum, and Psidium guajava for antibacterial and wound healing properties. Antibacterial properties of the extracts were studied against eleven wound isolates...
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| Veröffentlicht in: | Journal of ethnopharmacology 2006-03, Vol.104 (1-2), p.164-167 |
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| creator | Chah, K.F. Eze, C.A. Emuelosi, C.E. Esimone, C.O. |
| description | This study was conducted to evaluate methanolic extracts of Ageratum conyzoides, Anthocleista djalonensis, Napoleona imperialis, Ocimum gratissimum, and Psidium guajava for antibacterial and wound healing properties. Antibacterial properties of the extracts were studied against eleven wound isolates (Staphylococcus aureus (four strains), E. coli (two strains), Pseudomonas aeruginosa (one strain), Proteus spp. (three strains), and Shigella spp. (one strain)) using the well diffusion method. Wound healing properties of Ageratum conyzoides, Anthocleista djalonensis, Napoleonaea imperialis, and Ocimum gratissimum were determined using the excision wound model. Extract of Napoleona imperialis inhibited growth of all the test bacterial strains while Psidium guajava and Anthocleista djalonensis extracts prevented growth of 81.8 and 72.7% of the test organisms, respectively. Ageratum conyzoides and Ocimum gratissimum extracts did not inhibit growth of any of the test organisms. More than 90% wound healing was recorded in the extract and cicatrin® powder treated groups by 14 days post surgery, where as 72% healing was observed in the distilled water-treated group. The percentage healing in the distilled water-treated group was significantly different (P |
| doi_str_mv | 10.1016/j.jep.2005.08.070 |
| format | Article |
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Antibacterial properties of the extracts were studied against eleven wound isolates (Staphylococcus aureus (four strains), E. coli (two strains), Pseudomonas aeruginosa (one strain), Proteus spp. (three strains), and Shigella spp. (one strain)) using the well diffusion method. Wound healing properties of Ageratum conyzoides, Anthocleista djalonensis, Napoleonaea imperialis, and Ocimum gratissimum were determined using the excision wound model. Extract of Napoleona imperialis inhibited growth of all the test bacterial strains while Psidium guajava and Anthocleista djalonensis extracts prevented growth of 81.8 and 72.7% of the test organisms, respectively. Ageratum conyzoides and Ocimum gratissimum extracts did not inhibit growth of any of the test organisms. More than 90% wound healing was recorded in the extract and cicatrin® powder treated groups by 14 days post surgery, where as 72% healing was observed in the distilled water-treated group. The percentage healing in the distilled water-treated group was significantly different (P<0.001) from those of extract and antibiotic-treated groups.</description><identifier>ISSN: 0378-8741</identifier><identifier>EISSN: 1872-7573</identifier><identifier>DOI: 10.1016/j.jep.2005.08.070</identifier><identifier>PMID: 16226414</identifier><identifier>CODEN: JOETD7</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Ageratum conyzoides ; Animals ; Anthocleista djalonensis ; Anti-Bacterial Agents - isolation & purification ; Anti-Bacterial Agents - pharmacology ; Antibacterial ; antibacterial properties ; Biological and medical sciences ; Escherichia coli ; ethnobotany ; Extracts ; Female ; General pharmacology ; Healing ; Male ; Medical sciences ; Medicinal ; medicinal plants ; medicinal properties ; Methanol - pharmacology ; Microbial Sensitivity Tests - statistics & numerical data ; Napoleona imperialis ; Nigeria ; Ocimum gratissimum ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; plant extracts ; Plant Extracts - isolation & purification ; Plant Extracts - pharmacology ; Plant Leaves ; Plant Roots ; Plants ; Plants, Medicinal ; Proteus ; Pseudomonas aeruginosa ; Psidium guajava ; Rats ; Shigella ; Staphylococcus aureus ; traditional medicine ; Wound ; Wound Healing - drug effects ; Wound Healing - physiology ; wound treatment</subject><ispartof>Journal of ethnopharmacology, 2006-03, Vol.104 (1-2), p.164-167</ispartof><rights>2005 Elsevier Ireland Ltd</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c471t-fcb759bf2a198ae70defc494bfb3a647841a188ac61ee65450f2de2e160739d33</citedby><cites>FETCH-LOGICAL-c471t-fcb759bf2a198ae70defc494bfb3a647841a188ac61ee65450f2de2e160739d33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S037887410500615X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17568774$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16226414$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chah, K.F.</creatorcontrib><creatorcontrib>Eze, C.A.</creatorcontrib><creatorcontrib>Emuelosi, C.E.</creatorcontrib><creatorcontrib>Esimone, C.O.</creatorcontrib><title>Antibacterial and wound healing properties of methanolic extracts of some Nigerian medicinal plants</title><title>Journal of ethnopharmacology</title><addtitle>J Ethnopharmacol</addtitle><description>This study was conducted to evaluate methanolic extracts of Ageratum conyzoides, Anthocleista djalonensis, Napoleona imperialis, Ocimum gratissimum, and Psidium guajava for antibacterial and wound healing properties. Antibacterial properties of the extracts were studied against eleven wound isolates (Staphylococcus aureus (four strains), E. coli (two strains), Pseudomonas aeruginosa (one strain), Proteus spp. (three strains), and Shigella spp. (one strain)) using the well diffusion method. Wound healing properties of Ageratum conyzoides, Anthocleista djalonensis, Napoleonaea imperialis, and Ocimum gratissimum were determined using the excision wound model. Extract of Napoleona imperialis inhibited growth of all the test bacterial strains while Psidium guajava and Anthocleista djalonensis extracts prevented growth of 81.8 and 72.7% of the test organisms, respectively. Ageratum conyzoides and Ocimum gratissimum extracts did not inhibit growth of any of the test organisms. More than 90% wound healing was recorded in the extract and cicatrin® powder treated groups by 14 days post surgery, where as 72% healing was observed in the distilled water-treated group. The percentage healing in the distilled water-treated group was significantly different (P<0.001) from those of extract and antibiotic-treated groups.</description><subject>Ageratum conyzoides</subject><subject>Animals</subject><subject>Anthocleista djalonensis</subject><subject>Anti-Bacterial Agents - isolation & purification</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Antibacterial</subject><subject>antibacterial properties</subject><subject>Biological and medical sciences</subject><subject>Escherichia coli</subject><subject>ethnobotany</subject><subject>Extracts</subject><subject>Female</subject><subject>General pharmacology</subject><subject>Healing</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicinal</subject><subject>medicinal plants</subject><subject>medicinal properties</subject><subject>Methanol - pharmacology</subject><subject>Microbial Sensitivity Tests - statistics & numerical data</subject><subject>Napoleona imperialis</subject><subject>Nigeria</subject><subject>Ocimum gratissimum</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>plant extracts</subject><subject>Plant Extracts - isolation & purification</subject><subject>Plant Extracts - pharmacology</subject><subject>Plant Leaves</subject><subject>Plant Roots</subject><subject>Plants</subject><subject>Plants, Medicinal</subject><subject>Proteus</subject><subject>Pseudomonas aeruginosa</subject><subject>Psidium guajava</subject><subject>Rats</subject><subject>Shigella</subject><subject>Staphylococcus aureus</subject><subject>traditional medicine</subject><subject>Wound</subject><subject>Wound Healing - drug effects</subject><subject>Wound Healing - physiology</subject><subject>wound treatment</subject><issn>0378-8741</issn><issn>1872-7573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1v1DAQhi1ERZfCD-ACucAtYZw4Hq84VRVfUlUO0LPlOOOtV1kn2F7a_nu87Eq9cbEl63lfzTxm7A2HhgOXH7fNlpamBegbUA0gPGMrrrCtscfuOVtBh6pWKPg5e5nSFgCQC3jBzrlsWym4WDF7GbIfjM0UvZkqE8bqft6X847M5MOmWuK8UMyeUjW7akf5zoR58raihxxL7t9zmndU3fjNoSQUaPTWh1K3TCbk9IqdOTMlen26L9jtl8-_rr7V1z--fr-6vK6tQJ5rZwfs14NrDV8rQwgjOSvWYnBDZ6RAJbjhShkrOZHsRQ-uHaklLgG79dh1F-zDsbfM_HtPKeudT5amMgTN-6QlSqkk9AXkR9DGOaVITi_R70x81Bz0waze6mJWH8xqULqYLZm3p_L9UBZ8SpxUFuD9CTDJmslFE6xPTxz2UiEeuHdHzplZm00szO3PFnhXfqfDXmEhPh0JKrL-eIo6WU_BFq2RbNbj7P8z6F_Ap6Dr</recordid><startdate>20060308</startdate><enddate>20060308</enddate><creator>Chah, K.F.</creator><creator>Eze, C.A.</creator><creator>Emuelosi, C.E.</creator><creator>Esimone, C.O.</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20060308</creationdate><title>Antibacterial and wound healing properties of methanolic extracts of some Nigerian medicinal plants</title><author>Chah, K.F. ; Eze, C.A. ; Emuelosi, C.E. ; Esimone, C.O.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-fcb759bf2a198ae70defc494bfb3a647841a188ac61ee65450f2de2e160739d33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Ageratum conyzoides</topic><topic>Animals</topic><topic>Anthocleista djalonensis</topic><topic>Anti-Bacterial Agents - isolation & purification</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Antibacterial</topic><topic>antibacterial properties</topic><topic>Biological and medical sciences</topic><topic>Escherichia coli</topic><topic>ethnobotany</topic><topic>Extracts</topic><topic>Female</topic><topic>General pharmacology</topic><topic>Healing</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicinal</topic><topic>medicinal plants</topic><topic>medicinal properties</topic><topic>Methanol - pharmacology</topic><topic>Microbial Sensitivity Tests - statistics & numerical data</topic><topic>Napoleona imperialis</topic><topic>Nigeria</topic><topic>Ocimum gratissimum</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>plant extracts</topic><topic>Plant Extracts - isolation & purification</topic><topic>Plant Extracts - pharmacology</topic><topic>Plant Leaves</topic><topic>Plant Roots</topic><topic>Plants</topic><topic>Plants, Medicinal</topic><topic>Proteus</topic><topic>Pseudomonas aeruginosa</topic><topic>Psidium guajava</topic><topic>Rats</topic><topic>Shigella</topic><topic>Staphylococcus aureus</topic><topic>traditional medicine</topic><topic>Wound</topic><topic>Wound Healing - drug effects</topic><topic>Wound Healing - physiology</topic><topic>wound treatment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chah, K.F.</creatorcontrib><creatorcontrib>Eze, C.A.</creatorcontrib><creatorcontrib>Emuelosi, C.E.</creatorcontrib><creatorcontrib>Esimone, C.O.</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of ethnopharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chah, K.F.</au><au>Eze, C.A.</au><au>Emuelosi, C.E.</au><au>Esimone, C.O.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antibacterial and wound healing properties of methanolic extracts of some Nigerian medicinal plants</atitle><jtitle>Journal of ethnopharmacology</jtitle><addtitle>J Ethnopharmacol</addtitle><date>2006-03-08</date><risdate>2006</risdate><volume>104</volume><issue>1-2</issue><spage>164</spage><epage>167</epage><pages>164-167</pages><issn>0378-8741</issn><eissn>1872-7573</eissn><coden>JOETD7</coden><abstract>This study was conducted to evaluate methanolic extracts of Ageratum conyzoides, Anthocleista djalonensis, Napoleona imperialis, Ocimum gratissimum, and Psidium guajava for antibacterial and wound healing properties. Antibacterial properties of the extracts were studied against eleven wound isolates (Staphylococcus aureus (four strains), E. coli (two strains), Pseudomonas aeruginosa (one strain), Proteus spp. (three strains), and Shigella spp. (one strain)) using the well diffusion method. Wound healing properties of Ageratum conyzoides, Anthocleista djalonensis, Napoleonaea imperialis, and Ocimum gratissimum were determined using the excision wound model. Extract of Napoleona imperialis inhibited growth of all the test bacterial strains while Psidium guajava and Anthocleista djalonensis extracts prevented growth of 81.8 and 72.7% of the test organisms, respectively. Ageratum conyzoides and Ocimum gratissimum extracts did not inhibit growth of any of the test organisms. More than 90% wound healing was recorded in the extract and cicatrin® powder treated groups by 14 days post surgery, where as 72% healing was observed in the distilled water-treated group. The percentage healing in the distilled water-treated group was significantly different (P<0.001) from those of extract and antibiotic-treated groups.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>16226414</pmid><doi>10.1016/j.jep.2005.08.070</doi><tpages>4</tpages></addata></record> |
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| ispartof | Journal of ethnopharmacology, 2006-03, Vol.104 (1-2), p.164-167 |
| issn | 0378-8741 1872-7573 |
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| subjects | Ageratum conyzoides Animals Anthocleista djalonensis Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antibacterial antibacterial properties Biological and medical sciences Escherichia coli ethnobotany Extracts Female General pharmacology Healing Male Medical sciences Medicinal medicinal plants medicinal properties Methanol - pharmacology Microbial Sensitivity Tests - statistics & numerical data Napoleona imperialis Nigeria Ocimum gratissimum Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments plant extracts Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Leaves Plant Roots Plants Plants, Medicinal Proteus Pseudomonas aeruginosa Psidium guajava Rats Shigella Staphylococcus aureus traditional medicine Wound Wound Healing - drug effects Wound Healing - physiology wound treatment |
| title | Antibacterial and wound healing properties of methanolic extracts of some Nigerian medicinal plants |
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