Antiulcerogenic activity of Alchornea castaneaefolia: Effects on somatostatin, gastrin and prostaglandin

The hydroethanolic extract of the leaves (HEL) and bark (HEB) obtained from Alchornea castaneaefolia (Euphorbiaceae) were investigated for their ability to prevent ulceration of the gastric mucosa in animal models. HEL (500 and 1000mg/kg) and HEB (1000mg/kg) significantly reduced the gastric injurie...

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Veröffentlicht in:	Journal of ethnopharmacology 2006-03, Vol.104 (1-2), p.215-224
Hauptverfasser:	Hiruma-Lima, Clélia Akiko, Calvo, Tamara Roberta, Rodrigues, Clenilson Martins, Andrade, Fábio Donizete Pezzuto, Vilegas, Wagner, Brito, Alba Regina Monteiro Souza
Format:	Artikel
Sprache:	eng
Schlagworte:	Alchornea Alchornea castaneaefolia Animals anti-ulcer activity Anti-Ulcer Agents - isolation & purification Anti-Ulcer Agents - pharmacology Anti-Ulcer Agents - therapeutic use Antiulcer activity bark Biological and medical sciences chemical constituents of plants Dose-Response Relationship, Drug Euphorbiaceae Flavonoids Gastrins - antagonists & inhibitors Gastrins - biosynthesis General pharmacology leaves Male Medical sciences medicinal plants medicinal properties Mice Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Bark plant extracts Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Leaves Prostaglandins - biosynthesis Rats Rats, Wistar Somatostatin - biosynthesis Stomach Ulcer - drug therapy Stomach Ulcer - metabolism stomach ulcers
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