Cocaine- and Amphetamine-Regulated Transcript Is Localized in Pituitary Lactotropes and Is Regulated during Lactation

Cocaine- and amphetamine-regulated transcript (CART) is a highly expressed peptide implicated in the regulation of feeding, reward and reinforcement, and stress-related behaviors. CART has been localized to discrete cell populations in the brain, gut, adrenal gland, and pancreas. In contrast, CART-p...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2006-03, Vol.147 (3), p.1213-1223
Hauptverfasser:	Smith, Sean M, Vaughan, Joan M, Donaldson, Cynthia J, Fernandez, Rosette E, Li, Chien, Chen, Alon, Vale, Wylie W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal glands Amphetamines Amphetamines - pharmacology Animals Antisera Biological and medical sciences Breastfeeding & lactation Bromocriptine Bromocriptine - pharmacology Cell culture Cells, Cultured Chromatography Chromatography, Gel Cocaine Cocaine - pharmacology Cocaine- and amphetamine-regulated transcript protein Dopamine Feeding behavior Female Fibers Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation Hormones Hypothalamus - metabolism Immunoblotting Immunohistochemistry In Situ Hybridization Lactation Localization Magnocellular neurons Male Medical sciences Models, Statistical Nerve Tissue Proteins - biosynthesis Nerve Tissue Proteins - physiology Neurons - metabolism Neuropharmacology Nuclei (cytology) Oxytocin Oxytocin - metabolism Pharmacology. Drug treatments Physiological effects Pituitary (anterior) Pituitary (posterior) Pituitary gland Pituitary Gland - metabolism Populations Prolactin Proteins Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Radioimmunoassay Rats Rats, Sprague-Dawley RNA, Messenger - metabolism Supraoptic nucleus Tissue Distribution Vasopressin Vertebrates: endocrinology
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