Differential Gene Expression as a Potential Classifier of 2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole-Sensitive and -Insensitive Cell Lines

2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole (5F-203) is a candidate antitumor agent empirically discovered with the aid of the National Cancer Institute (NCI) Anticancer Drug Screen. In an effort to determine whether basal expression of genes could be used to classify cell sensitivity to this a...

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Veröffentlicht in:	Molecular pharmacology 2006-03, Vol.69 (3), p.737-748
Hauptverfasser:	Wallqvist, Anders, Connelly, John, Sausville, Edward A, Covell, David G, Monks, Anne
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor - drug effects Cell Line, Tumor - metabolism Drug Resistance, Neoplasm - genetics Drug Screening Assays, Antitumor - methods Gene Expression Gene Expression Profiling Humans Thiazoles - pharmacology
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