Nature of "Tau" immunoreactivity in normal myonuclei and inclusion body myositis

Sarcoplasmic accumulation of phosphorylated‐tau has been widely stated to occur in and contribute to the pathogenesis of muscle disease in inclusion body myositis. Twenty inflammatory myopathy and 10 normal muscle samples along with a range of other tissues were stained with anti‐“tau” antibodies (t...

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Veröffentlicht in:	Muscle & nerve 2009-10, Vol.40 (4), p.520-528
Hauptverfasser:	Salajegheh, Mohammad, Pinkus, Jack L., Nazareno, Remedios, Amato, Anthony A., Parker, Kenneth C., Greenberg, Steven A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - chemistry Antibody Specificity Biological and medical sciences Blotting, Western Cardiovascular system Cell Nucleus - metabolism Cell Nucleus - pathology Cross Reactions Diseases of striated muscles. Neuromuscular diseases Fluorescent Antibody Technique Humans Immunohistochemistry inclusion body myositis Investigative techniques, diagnostic techniques (general aspects) Medical sciences Microdissection Muscle Cells - metabolism Muscle Cells - pathology myonuclei Myositis, Inclusion Body - metabolism Myositis, Inclusion Body - pathology neurofilament H Neurology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Phosphorylation pS422 Sarcoplasmic Reticulum - metabolism Sarcoplasmic Reticulum - pathology SMI-31 tau tau Proteins - immunology tau Proteins - metabolism
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