Lysophosphatidylserine Stimulates L2071 Mouse Fibroblast Chemotactic Migration via a Process Involving Pertussis Toxin-Sensitive Trimeric G-Proteins

Lysophosphatidylserine (LPS) may be generated after phosphatidylserine-specific phospholipase A2 activation. However, the effects of LPS on cellular activities and the identities of its target molecules have not been fully elucidated. In this study, we observed that LPS stimulates an intracellular c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular pharmacology 2006-03, Vol.69 (3), p.1066-1073
Hauptverfasser:	Park, Kyoung Sun, Lee, Ha-Young, Kim, Mi-Kyoung, Shin, Eun Ha, Jo, Seong Ho, Kim, Sang Doo, Im, Dong-Soon, Bae, Yoe-Sik
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors Chemotaxis Enzyme Activation Estrenes - pharmacology Extracellular Signal-Regulated MAP Kinases - metabolism Fibroblasts - drug effects Fibroblasts - metabolism Fibroblasts - physiology Flavonoids - pharmacology GTP-Binding Protein alpha Subunits, Gi-Go - antagonists & inhibitors GTP-Binding Protein alpha Subunits, Gi-Go - physiology Lysophospholipids - pharmacology Mice p38 Mitogen-Activated Protein Kinases - metabolism Pertussis Toxin - pharmacology Phosphodiesterase Inhibitors - pharmacology Phosphorylation Proto-Oncogene Proteins c-akt - metabolism Pyrrolidinones - pharmacology Receptors, Lysophosphatidic Acid - antagonists & inhibitors Sphingosine - analogs & derivatives Sphingosine - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!