Evolutionary changes to transthyretin: developmentally regulated and tissue-specific gene expression

A survey of the expression of the transthyretin and thyroxine-binding globulin genes in various species during development provides clues as to how the present thyroid hormone distribution network in extracellular compartments developed during vertebrate evolution. Albumin may be the 'oldest�...

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Veröffentlicht in:	The FEBS journal 2009-10, Vol.276 (19), p.5357-5366
Hauptverfasser:	Yamauchi, Kiyoshi, Ishihara, Akinori
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Binding sites Biochemistry developmental regulation DNA - genetics DNA - metabolism Evolution, Molecular Evolutionary biology Gene Expression Profiling Gene Expression Regulation, Developmental Genetics Hormones Humans Liver - metabolism prealbumin Prealbumin - genetics Prealbumin - metabolism Promoter Regions, Genetic thyroid hormone Thyroid Hormones - metabolism Thyroxine-Binding Proteins - genetics Thyroxine-Binding Proteins - metabolism Tissue Distribution tissue specificity Transcription Factors - metabolism transcriptional control transthyretin Vertebrates - genetics Vertebrates - growth & development Vertebrates - metabolism
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