Association between high collagenase-3 expression levels and poor prognosis in patients with head and neck cancer

Background. Squamous cell carcinoma of the head and neck (HNSCC) is a common cancer type. The ability for curative treatment with surgery and radiotherapy (RT) is usually highly dependent on tumor stage at the time of diagnosis. Methods. The purpose of this study was to determine whether the express...

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Veröffentlicht in:	Head & neck 2006-03, Vol.28 (3), p.225-234
Hauptverfasser:	Luukkaa, Marjaana, Vihinen, Pia, Kronqvist, Pauliina, Vahlberg, Tero, Pyrhönen, Seppo, Kähäri, Veli-Matti, Grénman, Reidar
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Carcinoma, Squamous Cell - enzymology Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - therapy Collagenases - metabolism Female head/neck squamous cell carcinoma Humans Male Matrix Metalloproteinase 13 Medical sciences MMPs Mouth Neoplasms - enzymology Mouth Neoplasms - mortality Mouth Neoplasms - therapy Neoplasm Recurrence, Local - enzymology Otorhinolaryngology (head neck, general aspects and miscellaneous) Otorhinolaryngology. Stomatology Pharyngeal Neoplasms - enzymology Pharyngeal Neoplasms - mortality Pharyngeal Neoplasms - therapy Prognosis prognostic factors Radiotherapy, Adjuvant Tumors
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