Characterization and expression analysis of TNF-related apoptosis inducing ligand (TRAIL) in grass carp Ctenopharyngodon idella

TRAIL (Apo2 ligand) described as a type II transmembrane protein belonging to the TNF superfamily can induce apoptotic cell death in a variety of cell types. In the present study, a putative cDNA sequence encoding the 299 amino acids of TRAIL (GC-TRAIL) and its genomic organization were identified i...

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Veröffentlicht in:	Veterinary Immunology and Immunopathology 2006-03, Vol.110 (1), p.51-63
Hauptverfasser:	Chang, M.X., Nie, P., Xie, H.X., Wang, G.L., Gao, Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence amino acid sequences animal tissues Animals apoptosis Apoptosis Regulatory Proteins - biosynthesis Apoptosis Regulatory Proteins - genetics Apoptosis Regulatory Proteins - immunology Base Sequence Carps - genetics Carps - immunology Carps - metabolism Cloning, Molecular complementary DNA Ctenopharyngodon idella Danio rerio DNA, Complementary - genetics Expression freshwater fish gene expression Genome Grass carp Membrane Glycoproteins - biosynthesis Membrane Glycoproteins - genetics Membrane Glycoproteins - immunology Molecular Sequence Data nucleotide sequences Phylogeny Promoter promoter regions Promoter Regions, Genetic Reverse Transcriptase Polymerase Chain Reaction - veterinary Sequence Alignment sequence analysis Sequence Analysis, DNA TNF-Related Apoptosis-Inducing Ligand TRAIL transmembrane proteins Tumor Necrosis Factor-alpha - biosynthesis Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - immunology tumor necrosis factors
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