Primary progressive freezing gait : A syndrome with many causes
Primary progressive freezing gait (PPFG) is characterized by early gait freezing and a stereotyped progression. Of nine patients followed up for 6 to 16 years, two were diagnosed pathologically: pallidonigroluysian degeneration (PNLD) and diffuse Lewy body disease. Four others evolved clinically int...
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| Veröffentlicht in: | Neurology 2006-02, Vol.66 (3), p.411-414 |
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| creator | FACTOR, Stewart A HIGGINS, Donald S JIANG QIAN |
| description | Primary progressive freezing gait (PPFG) is characterized by early gait freezing and a stereotyped progression. Of nine patients followed up for 6 to 16 years, two were diagnosed pathologically: pallidonigroluysian degeneration (PNLD) and diffuse Lewy body disease. Four others evolved clinically into progressive supranuclear palsy and corticobasal degeneration. PPFG is not a distinct disorder but a syndrome with diverse causes. Long-term follow-up (> or =10 years) and postmortem are required for accurate diagnosis. PNLD may be the primary form of disease. |
| doi_str_mv | 10.1212/01.wnl.0000196469.52995.ab |
| format | Article |
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Of nine patients followed up for 6 to 16 years, two were diagnosed pathologically: pallidonigroluysian degeneration (PNLD) and diffuse Lewy body disease. Four others evolved clinically into progressive supranuclear palsy and corticobasal degeneration. PPFG is not a distinct disorder but a syndrome with diverse causes. Long-term follow-up (> or =10 years) and postmortem are required for accurate diagnosis. 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Of nine patients followed up for 6 to 16 years, two were diagnosed pathologically: pallidonigroluysian degeneration (PNLD) and diffuse Lewy body disease. Four others evolved clinically into progressive supranuclear palsy and corticobasal degeneration. PPFG is not a distinct disorder but a syndrome with diverse causes. Long-term follow-up (> or =10 years) and postmortem are required for accurate diagnosis. PNLD may be the primary form of disease.</description><subject>Aged</subject><subject>Amygdala - pathology</subject><subject>Basal Ganglia - pathology</subject><subject>Biological and medical sciences</subject><subject>Cerebral Cortex - pathology</subject><subject>Chromosome aberrations</subject><subject>Female</subject><subject>Gait</subject><subject>Globus Pallidus - pathology</subject><subject>Humans</subject><subject>Lewy Body Disease - complications</subject><subject>Lewy Body Disease - pathology</subject><subject>Male</subject><subject>Malformations of the nervous system</subject><subject>Medical genetics</subject><subject>Medical sciences</subject><subject>Movement Disorders - etiology</subject><subject>Movement Disorders - physiopathology</subject><subject>Neurodegenerative Diseases - complications</subject><subject>Neurodegenerative Diseases - pathology</subject><subject>Neurology</subject><subject>Substantia Nigra</subject><subject>Supranuclear Palsy, Progressive - complications</subject><subject>Supranuclear Palsy, Progressive - pathology</subject><issn>0028-3878</issn><issn>1526-632X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkF1LwzAUhoMobk7_ggRB71pz0iZpvJEx_IKBXih4F06zZFbabiadY_56qxvs3Jyb5z0fDyEXwFLgwK8ZpOu2TllfoGUudSq41iLF8oAMQXCZyIy_H5IhY7xIskIVA3IS42ePC670MRmAzJXUOR-S25dQNRg2dBkW8-BirL4d9cG5n6qd0zlWHb2hYxo37SwsGkfXVfdBG2w31OIqunhKjjzW0Z3t-oi83d-9Th6T6fPD02Q8TWyWqy6xqP1MQKm8FCA8MFtwZNJaWyoHCJzn3CuhcvRCOlsojYznyDnj2oFj2Yhcbef2d36tXOxMU0Xr6hpbt1hFI5UUUmjowZstaMMixuC8WW4_NMDMnz7DwPT6zF6f-ddnsOzD57stq7Jxs31056sHLncARou1D9jaKu45JRgAY9kv-KR5tQ</recordid><startdate>20060214</startdate><enddate>20060214</enddate><creator>FACTOR, Stewart A</creator><creator>HIGGINS, Donald S</creator><creator>JIANG QIAN</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20060214</creationdate><title>Primary progressive freezing gait : A syndrome with many causes</title><author>FACTOR, Stewart A ; HIGGINS, Donald S ; JIANG QIAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c347t-ca9fd51b7f6515f10c82a06cccb7e1a12242f7574af56ec879a024a22029e1e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Aged</topic><topic>Amygdala - pathology</topic><topic>Basal Ganglia - pathology</topic><topic>Biological and medical sciences</topic><topic>Cerebral Cortex - pathology</topic><topic>Chromosome aberrations</topic><topic>Female</topic><topic>Gait</topic><topic>Globus Pallidus - pathology</topic><topic>Humans</topic><topic>Lewy Body Disease - complications</topic><topic>Lewy Body Disease - pathology</topic><topic>Male</topic><topic>Malformations of the nervous system</topic><topic>Medical genetics</topic><topic>Medical sciences</topic><topic>Movement Disorders - etiology</topic><topic>Movement Disorders - physiopathology</topic><topic>Neurodegenerative Diseases - complications</topic><topic>Neurodegenerative Diseases - pathology</topic><topic>Neurology</topic><topic>Substantia Nigra</topic><topic>Supranuclear Palsy, Progressive - complications</topic><topic>Supranuclear Palsy, Progressive - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>FACTOR, Stewart A</creatorcontrib><creatorcontrib>HIGGINS, Donald S</creatorcontrib><creatorcontrib>JIANG QIAN</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>FACTOR, Stewart A</au><au>HIGGINS, Donald S</au><au>JIANG QIAN</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary progressive freezing gait : A syndrome with many causes</atitle><jtitle>Neurology</jtitle><addtitle>Neurology</addtitle><date>2006-02-14</date><risdate>2006</risdate><volume>66</volume><issue>3</issue><spage>411</spage><epage>414</epage><pages>411-414</pages><issn>0028-3878</issn><eissn>1526-632X</eissn><coden>NEURAI</coden><abstract>Primary progressive freezing gait (PPFG) is characterized by early gait freezing and a stereotyped progression. 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| ispartof | Neurology, 2006-02, Vol.66 (3), p.411-414 |
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| source | Journals@Ovid Complete - AutoHoldings; MEDLINE; Alma/SFX Local Collection |
| subjects | Aged Amygdala - pathology Basal Ganglia - pathology Biological and medical sciences Cerebral Cortex - pathology Chromosome aberrations Female Gait Globus Pallidus - pathology Humans Lewy Body Disease - complications Lewy Body Disease - pathology Male Malformations of the nervous system Medical genetics Medical sciences Movement Disorders - etiology Movement Disorders - physiopathology Neurodegenerative Diseases - complications Neurodegenerative Diseases - pathology Neurology Substantia Nigra Supranuclear Palsy, Progressive - complications Supranuclear Palsy, Progressive - pathology |
| title | Primary progressive freezing gait : A syndrome with many causes |
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