Cancer-related Overexpression of the Peripheral-type Benzodiazepine Receptor and Cytostatic Anticancer Effects of Ginkgo biloba Extract (EGb 761)

The peripheral-type benzodiazepine receptor (PBR) is an 18-kDa high affinity drug- and cholesterol-binding protein that is involved in various cell functions, including cell proliferation and apoptosis. PBR was shown to be overexpressed in certain types of malignant human tumors and cancer cell line...

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Veröffentlicht in:	Anticancer research 2006-01, Vol.26 (1A), p.9-22
Hauptverfasser:	PRETNER, Ewald, AMRI, Hakima, WENPING LI, BROWN, Rachel, LIN, Chin-Shoou, MAKARIOU, Erini, DEFEUDIS, Francis V, DRIEU, Katy, PAPADOPOULOS, Vassilios
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Growth Processes - physiology Cell Line, Tumor Cell Survival - physiology Estrogen Receptor alpha - biosynthesis Estrogen Receptor beta - biosynthesis Female Ginkgo biloba Humans Immunohistochemistry Medical sciences Mice Mice, Nude Neoplasms - drug therapy Neoplasms - genetics Neoplasms - metabolism Plant Extracts - pharmacology Polymerase Chain Reaction Radioligand Assay Receptors, GABA - biosynthesis Receptors, GABA - genetics Receptors, GABA - metabolism RNA, Messenger - biosynthesis RNA, Messenger - genetics Tumors Xenograft Model Antitumor Assays
Online-Zugang:	Volltext
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