Expression of alpha1-adrenoceptors on thymic cells and their role in fine tuning of thymopoiesis

The study was undertaken to explore: i) the presence of alpha(1)-adrenoceptors (AR) on thymic lymphoid and non-lymphoid cells and ii) their putative role in T-cell development. The expression of alpha(1)-AR on thymic cells was assessed using both immunohistochemistry and flow cytometric analyses, wh...

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Veröffentlicht in:	Journal of neuroimmunology 2009-09, Vol.214 (1-2), p.55-66
Hauptverfasser:	Pesić, V, Kosec, D, Radojević, K, Pilipović, I, Perisić, M, Vidić-Danković, B, Leposavić, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Antagonists - pharmacology Animals Apoptosis - drug effects CD4 Antigens - analysis Cell Proliferation - drug effects Flow Cytometry Fluorescent Antibody Technique Gene Expression Immunohistochemistry Interleukin-2 Receptor alpha Subunit - analysis Male NK Cell Lectin-Like Receptor Subfamily B - analysis Piperazines - pharmacology Rats Rats, Wistar Receptors, Adrenergic, alpha-1 - metabolism Receptors, Adrenergic, beta - metabolism T-Lymphocytes - drug effects T-Lymphocytes - immunology Thy-1 Antigens - drug effects Thy-1 Antigens - metabolism Thymus Gland - cytology Thymus Gland - drug effects Thymus Gland - metabolism Thymus Gland - physiology
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