An Open-label Study Adding Creatine Monohydrate to Ongoing Medical Regimens in Patients with the Fibromyalgia Syndrome
Fibromyalgia is an ill‐defined condition that causes pain and disability but still lacks effective treatment. The aim of this open‐label study was to assess the efficacy of administering a food supplement, creatine monohydrate, in an “add on” to existing therapies in patients with fibromyalgia. This...
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| Veröffentlicht in: | Annals of the New York Academy of Sciences 2009-09, Vol.1173 (1), p.829-836 |
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| container_title | Annals of the New York Academy of Sciences |
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| creator | Leader, Avi Amital, Daniella Rubinow, Alan Amital, Howard |
| description | Fibromyalgia is an ill‐defined condition that causes pain and disability but still lacks effective treatment. The aim of this open‐label study was to assess the efficacy of administering a food supplement, creatine monohydrate, in an “add on” to existing therapies in patients with fibromyalgia. This study included 30 patients with fibromyalgia. After 8 weeks of receiving creatine, we witnessed a significant improvement in parameters reflecting severity of fibromyalgia, quality of life and sleep, disability, and pain. These results deteriorated 4 weeks after stopping creatine therapy. The findings of this study are preliminary and limited due to the small sample and relatively high rate of dropouts. |
| doi_str_mv | 10.1111/j.1749-6632.2009.04811.x |
| format | Article |
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The aim of this open‐label study was to assess the efficacy of administering a food supplement, creatine monohydrate, in an “add on” to existing therapies in patients with fibromyalgia. This study included 30 patients with fibromyalgia. After 8 weeks of receiving creatine, we witnessed a significant improvement in parameters reflecting severity of fibromyalgia, quality of life and sleep, disability, and pain. These results deteriorated 4 weeks after stopping creatine therapy. The findings of this study are preliminary and limited due to the small sample and relatively high rate of dropouts.</description><subject>anxiety</subject><subject>Creatine</subject><subject>Creatine - administration & dosage</subject><subject>Creatine - therapeutic use</subject><subject>depression</subject><subject>Deterioration</subject><subject>Disabilities</subject><subject>Drug Therapy, Combination</subject><subject>Effectiveness</subject><subject>Female</subject><subject>fibromyalgia</subject><subject>Fibromyalgia - drug therapy</subject><subject>Fibromyalgia - physiopathology</subject><subject>Humans</subject><subject>Pain</subject><subject>Pain Measurement - methods</subject><subject>Patient Compliance - statistics & numerical data</subject><subject>Patients</subject><subject>Quality of Life</subject><subject>Receiving</subject><subject>Severity of Illness Index</subject><subject>Sleep - drug effects</subject><subject>Surveys and Questionnaires</subject><subject>Syndrome</subject><subject>Therapy</subject><subject>Treatment Outcome</subject><issn>0077-8923</issn><issn>1749-6632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkUuP0zAUhS0EYsrAX0BeITYpfsSxvUGqKmYY6EwR5SFWlpPctC6JU-J0pvn3OLQadgze2Nb9zrnSOQhhSqY0njfbKZWpTrKMsykjRE9JqiidHh6hyf3gMZoQImWiNONn6FkIW0IoU6l8is6olkIxLibodubxcgc-qW0ONV71-3LAs7J0fo3nHdjeecDXrW83Q9nZHnDf4qVft-P8GkpX2Bp_hrVrwAfsPP4UFeD7gO9cv8H9BvCFy7u2GWy9dhavBl_GHzxHTypbB3hxus_R14t3X-bvk8Xy8mo-WySFIJwmJQguCqE51Vle5dxaQYGoKqWQEV7YXGegKsuplNpKyTSrilxBqVmeRqji5-jV0XfXtb_2EHrTuFBAXVsP7T6YTGYi1Vw-CPJUx_ikiODrf4JUESJIDJg-jEoVUUnTLKLqiBZdG0IHldl1rrHdYCgxY-Vma8ZmzdisGSs3fyo3hyh9edqyzxso_wpPHUfg7RG4czUM_21sbn7MVuMzGiRHAxd6ONwb2O5nzI9LYb7fXBqWyW8fGFuYj_w3F1TJNg</recordid><startdate>200909</startdate><enddate>200909</enddate><creator>Leader, Avi</creator><creator>Amital, Daniella</creator><creator>Rubinow, Alan</creator><creator>Amital, Howard</creator><general>Blackwell Publishing Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7ST</scope><scope>C1K</scope><scope>SOI</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>200909</creationdate><title>An Open-label Study Adding Creatine Monohydrate to Ongoing Medical Regimens in Patients with the Fibromyalgia Syndrome</title><author>Leader, Avi ; 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| identifier | ISSN: 0077-8923 |
| ispartof | Annals of the New York Academy of Sciences, 2009-09, Vol.1173 (1), p.829-836 |
| issn | 0077-8923 1749-6632 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | anxiety Creatine Creatine - administration & dosage Creatine - therapeutic use depression Deterioration Disabilities Drug Therapy, Combination Effectiveness Female fibromyalgia Fibromyalgia - drug therapy Fibromyalgia - physiopathology Humans Pain Pain Measurement - methods Patient Compliance - statistics & numerical data Patients Quality of Life Receiving Severity of Illness Index Sleep - drug effects Surveys and Questionnaires Syndrome Therapy Treatment Outcome |
| title | An Open-label Study Adding Creatine Monohydrate to Ongoing Medical Regimens in Patients with the Fibromyalgia Syndrome |
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