IL-18 Activity in Systemic Lupus Erythematosus

Interleukin‐18 (IL‐18) is an inflammation‐related cytokine that plays a central role both in innate defense reactions and in Th1 activation and specific immune responses. Increased levels of IL‐18 can be detected in biological fluids and organs of individuals affected by several autoimmune pathologi...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2009-09, Vol.1173 (1), p.301-309
Hauptverfasser:	Favilli, Flavia, Anzilotti, Consuelo, Martinelli, Lucia, Quattroni, Paola, De Martino, Salvatore, Pratesi, Federico, Neumann, Detlef, Beermann, Silke, Novick, Daniela, Dinarello, Charles A., Boraschi, Diana, Migliorini, Paola
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Animals Chronic conditions Circulating Correlation Damage Failure Gene Expression Profiling Humans Intercellular Signaling Peptides and Proteins - genetics Intercellular Signaling Peptides and Proteins - metabolism interleukin 18 Interleukin-16 - blood Interleukin-16 - genetics Interleukin-16 - metabolism Kidney - metabolism Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - genetics Lupus Erythematosus, Systemic - metabolism Lymph Nodes - metabolism Mice Mice, Inbred MRL lpr Organs regulation of inflammation Risk systemic lupus erythematosus
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