The Transcription Factor Hepatocyte Nuclear Factor-6 Controls the Development of Pancreatic Ducts in the Mouse

Background & Aims: A number of hereditary polycystic diseases are associated with formation of cysts within the pancreatic ducts. The cysts result from abnormal tubulogenesis, but how normal pancreatic duct development is controlled remains poorly understood. Here, we investigate the transcripti...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2006-02, Vol.130 (2), p.532-541
Hauptverfasser:	Pierreux, Christophe E., Poll, Aurélie V., Kemp, Caroline R., Clotman, Frédéric, Maestro, Miguel A., Cordi, Sabine, Ferrer, Jorge, Leyns, Luc, Rousseau, Guy G., Lemaigre, Frédéric P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence DNA Primers Embryonic Development Gene Expression Regulation, Developmental Hepatocyte Nuclear Factor 6 - deficiency Hepatocyte Nuclear Factor 6 - genetics Mice Mice, Knockout Morphogenesis Pancreatic Diseases - genetics Pancreatic Ducts - embryology Pancreatic Ducts - growth & development Reverse Transcriptase Polymerase Chain Reaction
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