Unique patterns of FOS, phospho-CREB and BrdU immunoreactivity in the female rat brain following chronic stress and citalopram treatment

Affective disorders are common psychiatric illnesses characterized by marked gender-related prevalence. Recent evidence links chronic stress and dysregulation of neurotrophin signaling with the development of depression, while novel theories suggest that antidepressants may act by promoting intracel...

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Veröffentlicht in:	Neuropharmacology 2006-03, Vol.50 (4), p.428-440
Hauptverfasser:	Kuipers, S.D., Trentani, A., Westenbroek, C., Bramham, C.R., Korf, J., Kema, I.P., Ter Horst, G.J., Den Boer, J.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressive Agents, Second-Generation - therapeutic use BrdU Bromodeoxyuridine c- fos Citalopram Citalopram - therapeutic use Corticosterone - blood CREB-Binding Protein - drug effects CREB-Binding Protein - metabolism Electroshock Female Footshock Immunohistochemistry Male Phospho-CREB Proto-Oncogene Proteins c-fos - drug effects Proto-Oncogene Proteins c-fos - metabolism Rats Rats, Wistar Stress, Psychological - drug therapy Stress, Psychological - physiopathology Weight Gain - drug effects
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