Surveillance for Pediatric Deaths Associated with 2009 Pandemic Influenza A (H1N1) Virus Infection — United States, April–August 2009
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creator | Shannon, S Louie, J Siniscalchi, A Rico, E Richter, D Hernandez, R Lynfield, R McHugh, L Waters, C Lee, E Stoute, A Landers, K Bandy, U Pascoe, N Vernon, V Haupt, T Moore, C Schieve, L Peacock, G Boyle, C Honein, M Yeargin-Allsopp, M Trevathan, E Finelli, L Uyeki, T Dhara, R Fowlkes, A Christensen, D Jarquin, V |
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Because of this increased risk, the Advisory Committee on Immunization Practices (ACIP) has prioritized influenza prevention and treatment for children aged <5 years and for those with certain chronic medical and immunosuppressive conditions. CDC monitors child influenza deaths through its influenza-associated pediatric mortality reporting system. As of August 8, 2009, CDC had received reports of 477 deaths associated with 2009 pandemic influenza A (H1N1) in the United States, including 36 deaths among children aged <18 years. To characterize these cases, CDC analyzed data from April to August 2009. The results of that analysis indicated that, of 36 children who died, seven (19%) were aged <5 years, and 24 (67%) had one or more of the high-risk medical conditions. Twenty-two (92%) of the 24 children with high-risk medical conditions had neurodevelopmental conditions. Among 23 children with culture or pathology results reported, laboratory-confirmed bacterial coinfections were identified in 10 (43%), including all six children who 1) were aged >or=5 years, 2) had no recognized high-risk condition, and 3) had culture or pathology results reported. Early diagnosis of influenza can enable prompt initiation of antiviral therapy for children who are at greater risk or severely ill. Clinicians also should be aware of the potential for severe bacterial coinfections among children diagnosed with influenza and treat accordingly. All children aged >or=6 months and caregivers of children aged <6 months should receive influenza A (H1N1) 2009 monovalent vaccine when available.</description><identifier>ISSN: 0149-2195</identifier><identifier>EISSN: 1545-861X</identifier><identifier>PMID: 19730406</identifier><language>eng</language><publisher>United States: Centers for Disease Control and Prevention</publisher><subject>2009 AD ; Adolescent ; Bacterial Infections - complications ; Blood ; Child ; Child, Preschool ; Children ; Chronic Disease ; Death ; Demographic aspects ; Developmental delay ; Diseases ; Female ; H1N1 subtype influenza A virus ; Humans ; Infant ; Influenza A virus ; Influenza A Virus, H1N1 Subtype ; Influenza, Human - complications ; Influenza, Human - mortality ; Intensive care units ; Male ; Medical conditions ; Pandemics ; Pediatrics ; Population Surveillance ; Risk ; Sentinel health events ; Social aspects ; Swine influenza ; United States - epidemiology</subject><ispartof>MMWR. Morbidity and mortality weekly report, 2009-09, Vol.58 (34), p.941-947</ispartof><rights>COPYRIGHT 2009 U.S. Government Printing Office</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/23319101$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/23319101$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19730406$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shannon, S</creatorcontrib><creatorcontrib>Louie, J</creatorcontrib><creatorcontrib>Siniscalchi, A</creatorcontrib><creatorcontrib>Rico, E</creatorcontrib><creatorcontrib>Richter, D</creatorcontrib><creatorcontrib>Hernandez, R</creatorcontrib><creatorcontrib>Lynfield, R</creatorcontrib><creatorcontrib>McHugh, L</creatorcontrib><creatorcontrib>Waters, C</creatorcontrib><creatorcontrib>Lee, E</creatorcontrib><creatorcontrib>Stoute, A</creatorcontrib><creatorcontrib>Landers, K</creatorcontrib><creatorcontrib>Bandy, U</creatorcontrib><creatorcontrib>Pascoe, N</creatorcontrib><creatorcontrib>Vernon, V</creatorcontrib><creatorcontrib>Haupt, T</creatorcontrib><creatorcontrib>Moore, C</creatorcontrib><creatorcontrib>Schieve, L</creatorcontrib><creatorcontrib>Peacock, G</creatorcontrib><creatorcontrib>Boyle, C</creatorcontrib><creatorcontrib>Honein, M</creatorcontrib><creatorcontrib>Yeargin-Allsopp, M</creatorcontrib><creatorcontrib>Trevathan, E</creatorcontrib><creatorcontrib>Finelli, L</creatorcontrib><creatorcontrib>Uyeki, T</creatorcontrib><creatorcontrib>Dhara, R</creatorcontrib><creatorcontrib>Fowlkes, A</creatorcontrib><creatorcontrib>Christensen, D</creatorcontrib><creatorcontrib>Jarquin, V</creatorcontrib><creatorcontrib>Centers for Disease Control and Prevention (CDC)</creatorcontrib><title>Surveillance for Pediatric Deaths Associated with 2009 Pandemic Influenza A (H1N1) Virus Infection — United States, April–August 2009</title><title>MMWR. Morbidity and mortality weekly report</title><addtitle>MMWR Morb Mortal Wkly Rep</addtitle><description>Children aged <5 years or with certain chronic medical conditions are at increased risk for complications and death from influenza. Because of this increased risk, the Advisory Committee on Immunization Practices (ACIP) has prioritized influenza prevention and treatment for children aged <5 years and for those with certain chronic medical and immunosuppressive conditions. CDC monitors child influenza deaths through its influenza-associated pediatric mortality reporting system. As of August 8, 2009, CDC had received reports of 477 deaths associated with 2009 pandemic influenza A (H1N1) in the United States, including 36 deaths among children aged <18 years. To characterize these cases, CDC analyzed data from April to August 2009. The results of that analysis indicated that, of 36 children who died, seven (19%) were aged <5 years, and 24 (67%) had one or more of the high-risk medical conditions. Twenty-two (92%) of the 24 children with high-risk medical conditions had neurodevelopmental conditions. Among 23 children with culture or pathology results reported, laboratory-confirmed bacterial coinfections were identified in 10 (43%), including all six children who 1) were aged >or=5 years, 2) had no recognized high-risk condition, and 3) had culture or pathology results reported. Early diagnosis of influenza can enable prompt initiation of antiviral therapy for children who are at greater risk or severely ill. Clinicians also should be aware of the potential for severe bacterial coinfections among children diagnosed with influenza and treat accordingly. All children aged >or=6 months and caregivers of children aged <6 months should receive influenza A (H1N1) 2009 monovalent vaccine when available.</description><subject>2009 AD</subject><subject>Adolescent</subject><subject>Bacterial Infections - complications</subject><subject>Blood</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Chronic Disease</subject><subject>Death</subject><subject>Demographic aspects</subject><subject>Developmental delay</subject><subject>Diseases</subject><subject>Female</subject><subject>H1N1 subtype influenza A virus</subject><subject>Humans</subject><subject>Infant</subject><subject>Influenza A virus</subject><subject>Influenza A Virus, H1N1 Subtype</subject><subject>Influenza, Human - complications</subject><subject>Influenza, Human - mortality</subject><subject>Intensive care units</subject><subject>Male</subject><subject>Medical conditions</subject><subject>Pandemics</subject><subject>Pediatrics</subject><subject>Population Surveillance</subject><subject>Risk</subject><subject>Sentinel health events</subject><subject>Social aspects</subject><subject>Swine influenza</subject><subject>United States - epidemiology</subject><issn>0149-2195</issn><issn>1545-861X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkU1LHTEUhgdpqbe2P8GSlVjolHzN13LQtgrSCtbS3ZCbnLk3kptoPip25bbr9hf6S5rxqiiYLELOec5LeLJRzEjFq7Ktyc8XxQwT3pWUdNVm8TqEMzwthl8Vm6RrGOa4nhV_TpL_BdoYYSWg0Xl0DEqL6LVE-yDiMqA-BCdzCRS61HGJKMYdOhZWwSpDh3Y0CexvgXq0e0C-kvfoh_YpTA2QUTuLbq7_oVOrp4CTmHPCB9Sfe21urv_2aZFCvI18U7wchQnw9u7cKk4_f_q-d1AefftyuNcflQta8VjKjinFsIKOi7pVrGphziDfaMtrPqeSthWjFW0oUyCV5FzMW-gaXIuqFpSzrWJnnXvu3UWCEIeVDhImA-BSGOqmZm1LWAbLNbgQBgZtRxe9kAuw4IVxFkadyz0lmDSEMJz5j8_wed-KenZg59HAEoTJup1Jk7TwFHx39-Q0X4EasryV8FfD_TdmYHsNnIXo_EOfMka6nML-A5tHoec</recordid><startdate>20090904</startdate><enddate>20090904</enddate><creator>Shannon, S</creator><creator>Louie, J</creator><creator>Siniscalchi, A</creator><creator>Rico, E</creator><creator>Richter, D</creator><creator>Hernandez, R</creator><creator>Lynfield, R</creator><creator>McHugh, L</creator><creator>Waters, C</creator><creator>Lee, E</creator><creator>Stoute, A</creator><creator>Landers, K</creator><creator>Bandy, U</creator><creator>Pascoe, N</creator><creator>Vernon, V</creator><creator>Haupt, T</creator><creator>Moore, C</creator><creator>Schieve, L</creator><creator>Peacock, G</creator><creator>Boyle, C</creator><creator>Honein, M</creator><creator>Yeargin-Allsopp, M</creator><creator>Trevathan, E</creator><creator>Finelli, L</creator><creator>Uyeki, T</creator><creator>Dhara, R</creator><creator>Fowlkes, A</creator><creator>Christensen, D</creator><creator>Jarquin, V</creator><general>Centers for Disease Control and Prevention</general><general>U.S. Government Printing Office</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20090904</creationdate><title>Surveillance for Pediatric Deaths Associated with 2009 Pandemic Influenza A (H1N1) Virus Infection — United States, April–August 2009</title><author>Shannon, S ; Louie, J ; Siniscalchi, A ; Rico, E ; Richter, D ; Hernandez, R ; Lynfield, R ; McHugh, L ; Waters, C ; Lee, E ; Stoute, A ; Landers, K ; Bandy, U ; Pascoe, N ; Vernon, V ; Haupt, T ; Moore, C ; Schieve, L ; Peacock, G ; Boyle, C ; Honein, M ; Yeargin-Allsopp, M ; Trevathan, E ; Finelli, L ; Uyeki, T ; Dhara, R ; Fowlkes, A ; Christensen, D ; Jarquin, V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g254t-c93dd30de94a68d358eb3ee9428464b2c2853252723decdc44ab8e9706a56a243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>2009 AD</topic><topic>Adolescent</topic><topic>Bacterial Infections - complications</topic><topic>Blood</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Chronic Disease</topic><topic>Death</topic><topic>Demographic aspects</topic><topic>Developmental delay</topic><topic>Diseases</topic><topic>Female</topic><topic>H1N1 subtype influenza A virus</topic><topic>Humans</topic><topic>Infant</topic><topic>Influenza A virus</topic><topic>Influenza A Virus, H1N1 Subtype</topic><topic>Influenza, Human - complications</topic><topic>Influenza, Human - mortality</topic><topic>Intensive care units</topic><topic>Male</topic><topic>Medical conditions</topic><topic>Pandemics</topic><topic>Pediatrics</topic><topic>Population Surveillance</topic><topic>Risk</topic><topic>Sentinel health events</topic><topic>Social aspects</topic><topic>Swine influenza</topic><topic>United States - epidemiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Shannon, S</creatorcontrib><creatorcontrib>Louie, J</creatorcontrib><creatorcontrib>Siniscalchi, A</creatorcontrib><creatorcontrib>Rico, E</creatorcontrib><creatorcontrib>Richter, D</creatorcontrib><creatorcontrib>Hernandez, R</creatorcontrib><creatorcontrib>Lynfield, R</creatorcontrib><creatorcontrib>McHugh, L</creatorcontrib><creatorcontrib>Waters, C</creatorcontrib><creatorcontrib>Lee, E</creatorcontrib><creatorcontrib>Stoute, A</creatorcontrib><creatorcontrib>Landers, K</creatorcontrib><creatorcontrib>Bandy, U</creatorcontrib><creatorcontrib>Pascoe, N</creatorcontrib><creatorcontrib>Vernon, V</creatorcontrib><creatorcontrib>Haupt, T</creatorcontrib><creatorcontrib>Moore, C</creatorcontrib><creatorcontrib>Schieve, L</creatorcontrib><creatorcontrib>Peacock, G</creatorcontrib><creatorcontrib>Boyle, C</creatorcontrib><creatorcontrib>Honein, M</creatorcontrib><creatorcontrib>Yeargin-Allsopp, M</creatorcontrib><creatorcontrib>Trevathan, E</creatorcontrib><creatorcontrib>Finelli, L</creatorcontrib><creatorcontrib>Uyeki, T</creatorcontrib><creatorcontrib>Dhara, R</creatorcontrib><creatorcontrib>Fowlkes, A</creatorcontrib><creatorcontrib>Christensen, D</creatorcontrib><creatorcontrib>Jarquin, V</creatorcontrib><creatorcontrib>Centers for Disease Control and Prevention (CDC)</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>MMWR. Morbidity and mortality weekly report</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shannon, S</au><au>Louie, J</au><au>Siniscalchi, A</au><au>Rico, E</au><au>Richter, D</au><au>Hernandez, R</au><au>Lynfield, R</au><au>McHugh, L</au><au>Waters, C</au><au>Lee, E</au><au>Stoute, A</au><au>Landers, K</au><au>Bandy, U</au><au>Pascoe, N</au><au>Vernon, V</au><au>Haupt, T</au><au>Moore, C</au><au>Schieve, L</au><au>Peacock, G</au><au>Boyle, C</au><au>Honein, M</au><au>Yeargin-Allsopp, M</au><au>Trevathan, E</au><au>Finelli, L</au><au>Uyeki, T</au><au>Dhara, R</au><au>Fowlkes, A</au><au>Christensen, D</au><au>Jarquin, V</au><aucorp>Centers for Disease Control and Prevention (CDC)</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Surveillance for Pediatric Deaths Associated with 2009 Pandemic Influenza A (H1N1) Virus Infection — United States, April–August 2009</atitle><jtitle>MMWR. Morbidity and mortality weekly report</jtitle><addtitle>MMWR Morb Mortal Wkly Rep</addtitle><date>2009-09-04</date><risdate>2009</risdate><volume>58</volume><issue>34</issue><spage>941</spage><epage>947</epage><pages>941-947</pages><issn>0149-2195</issn><eissn>1545-861X</eissn><abstract>Children aged <5 years or with certain chronic medical conditions are at increased risk for complications and death from influenza. Because of this increased risk, the Advisory Committee on Immunization Practices (ACIP) has prioritized influenza prevention and treatment for children aged <5 years and for those with certain chronic medical and immunosuppressive conditions. CDC monitors child influenza deaths through its influenza-associated pediatric mortality reporting system. As of August 8, 2009, CDC had received reports of 477 deaths associated with 2009 pandemic influenza A (H1N1) in the United States, including 36 deaths among children aged <18 years. To characterize these cases, CDC analyzed data from April to August 2009. The results of that analysis indicated that, of 36 children who died, seven (19%) were aged <5 years, and 24 (67%) had one or more of the high-risk medical conditions. Twenty-two (92%) of the 24 children with high-risk medical conditions had neurodevelopmental conditions. Among 23 children with culture or pathology results reported, laboratory-confirmed bacterial coinfections were identified in 10 (43%), including all six children who 1) were aged >or=5 years, 2) had no recognized high-risk condition, and 3) had culture or pathology results reported. Early diagnosis of influenza can enable prompt initiation of antiviral therapy for children who are at greater risk or severely ill. Clinicians also should be aware of the potential for severe bacterial coinfections among children diagnosed with influenza and treat accordingly. All children aged >or=6 months and caregivers of children aged <6 months should receive influenza A (H1N1) 2009 monovalent vaccine when available.</abstract><cop>United States</cop><pub>Centers for Disease Control and Prevention</pub><pmid>19730406</pmid><tpages>7</tpages></addata></record> |
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subjects | 2009 AD Adolescent Bacterial Infections - complications Blood Child Child, Preschool Children Chronic Disease Death Demographic aspects Developmental delay Diseases Female H1N1 subtype influenza A virus Humans Infant Influenza A virus Influenza A Virus, H1N1 Subtype Influenza, Human - complications Influenza, Human - mortality Intensive care units Male Medical conditions Pandemics Pediatrics Population Surveillance Risk Sentinel health events Social aspects Swine influenza United States - epidemiology |
title | Surveillance for Pediatric Deaths Associated with 2009 Pandemic Influenza A (H1N1) Virus Infection — United States, April–August 2009 |
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