Iris metastasis as the first sign of small-cell lung carcinoma with metastatic involvement of the mediastinum
We present the case of small-cell lung carcinoma metastatic to the iris, the course of the disease and management options. A 69-year-old female was diagnosed with a solid, amelanotic iris mass in her left eye. Differential diagnostics and ancillary tests subsequently led to the diagnosis of dissemin...
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| Veröffentlicht in: | Klinická onkologie 2009, Vol.22 (4), p.179-182 |
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| creator | Jurecka, T Skorkovská, S Coupková, H Postránecká, V |
| description | We present the case of small-cell lung carcinoma metastatic to the iris, the course of the disease and management options.
A 69-year-old female was diagnosed with a solid, amelanotic iris mass in her left eye. Differential diagnostics and ancillary tests subsequently led to the diagnosis of disseminated small-cell lung carcinoma. Systemic chemotherapy was indicated after fine needle biopsy verification of metastatic lung cancer. Iris metastasis responded well to the chemotherapy, its regression was observed and secondary open-angle glaucoma was controlled as well. Good visual functions were preserved during the treatment.
Metastatic carcinoma of the iris may be the first sign of disseminated malignant disease. Small-cell lung carcinoma iris metastasis can be treated with chemotherapy. This treatment preserved visual functions, which enhanced the patient's quality of life. |
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A 69-year-old female was diagnosed with a solid, amelanotic iris mass in her left eye. Differential diagnostics and ancillary tests subsequently led to the diagnosis of disseminated small-cell lung carcinoma. Systemic chemotherapy was indicated after fine needle biopsy verification of metastatic lung cancer. Iris metastasis responded well to the chemotherapy, its regression was observed and secondary open-angle glaucoma was controlled as well. Good visual functions were preserved during the treatment.
Metastatic carcinoma of the iris may be the first sign of disseminated malignant disease. Small-cell lung carcinoma iris metastasis can be treated with chemotherapy. This treatment preserved visual functions, which enhanced the patient's quality of life.</description><identifier>ISSN: 0862-495X</identifier><identifier>PMID: 19731881</identifier><language>cze</language><publisher>Czech Republic</publisher><subject>Aged ; Female ; Humans ; Iris Neoplasms - secondary ; Lung Neoplasms - pathology ; Mediastinal Neoplasms - diagnosis ; Mediastinal Neoplasms - secondary ; Small Cell Lung Carcinoma - diagnosis ; Small Cell Lung Carcinoma - secondary</subject><ispartof>Klinická onkologie, 2009, Vol.22 (4), p.179-182</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19731881$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jurecka, T</creatorcontrib><creatorcontrib>Skorkovská, S</creatorcontrib><creatorcontrib>Coupková, H</creatorcontrib><creatorcontrib>Postránecká, V</creatorcontrib><title>Iris metastasis as the first sign of small-cell lung carcinoma with metastatic involvement of the mediastinum</title><title>Klinická onkologie</title><addtitle>Klin Onkol</addtitle><description>We present the case of small-cell lung carcinoma metastatic to the iris, the course of the disease and management options.
A 69-year-old female was diagnosed with a solid, amelanotic iris mass in her left eye. Differential diagnostics and ancillary tests subsequently led to the diagnosis of disseminated small-cell lung carcinoma. Systemic chemotherapy was indicated after fine needle biopsy verification of metastatic lung cancer. Iris metastasis responded well to the chemotherapy, its regression was observed and secondary open-angle glaucoma was controlled as well. Good visual functions were preserved during the treatment.
Metastatic carcinoma of the iris may be the first sign of disseminated malignant disease. Small-cell lung carcinoma iris metastasis can be treated with chemotherapy. This treatment preserved visual functions, which enhanced the patient's quality of life.</description><subject>Aged</subject><subject>Female</subject><subject>Humans</subject><subject>Iris Neoplasms - secondary</subject><subject>Lung Neoplasms - pathology</subject><subject>Mediastinal Neoplasms - diagnosis</subject><subject>Mediastinal Neoplasms - secondary</subject><subject>Small Cell Lung Carcinoma - diagnosis</subject><subject>Small Cell Lung Carcinoma - secondary</subject><issn>0862-495X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1UMtqwzAQ1KGlCWl-oejUmyGSLFk6ltBHIJBLDr2ZlS0lKpLsWnJK_742TZaFHZgHw96h5UYKWpSKfy7QOqWvzTSCVpzLB7QgqmJESrJEYTe4hIPJkKadICSczwZbN6SMkztF3FmcAnhfNMZ77Md4wg0MjYtdAPzj8vlmz67BLl46fzHBxDwb56hgWjfRLo7hEd1b8Mmsr3eFjm-vx-1HsT-877Yv-6LnJSmstVwJy2VrQClgVAvKGgK6LTclJ1woJRXVlBIutSGtZmXbSuCgBcgSLFuh5__Yfui-R5NyHVya20M03ZhqUQlWyUpOwqercNRTzbofXIDht779h_0BLs5jmQ</recordid><startdate>2009</startdate><enddate>2009</enddate><creator>Jurecka, T</creator><creator>Skorkovská, S</creator><creator>Coupková, H</creator><creator>Postránecká, V</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>2009</creationdate><title>Iris metastasis as the first sign of small-cell lung carcinoma with metastatic involvement of the mediastinum</title><author>Jurecka, T ; Skorkovská, S ; Coupková, H ; Postránecká, V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p541-fff596f58dea99a32b623c1abd404515699892b22158be1db34dd8a5ab6a84af3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>cze</language><creationdate>2009</creationdate><topic>Aged</topic><topic>Female</topic><topic>Humans</topic><topic>Iris Neoplasms - secondary</topic><topic>Lung Neoplasms - pathology</topic><topic>Mediastinal Neoplasms - diagnosis</topic><topic>Mediastinal Neoplasms - secondary</topic><topic>Small Cell Lung Carcinoma - diagnosis</topic><topic>Small Cell Lung Carcinoma - secondary</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jurecka, T</creatorcontrib><creatorcontrib>Skorkovská, S</creatorcontrib><creatorcontrib>Coupková, H</creatorcontrib><creatorcontrib>Postránecká, V</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Klinická onkologie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jurecka, T</au><au>Skorkovská, S</au><au>Coupková, H</au><au>Postránecká, V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Iris metastasis as the first sign of small-cell lung carcinoma with metastatic involvement of the mediastinum</atitle><jtitle>Klinická onkologie</jtitle><addtitle>Klin Onkol</addtitle><date>2009</date><risdate>2009</risdate><volume>22</volume><issue>4</issue><spage>179</spage><epage>182</epage><pages>179-182</pages><issn>0862-495X</issn><abstract>We present the case of small-cell lung carcinoma metastatic to the iris, the course of the disease and management options.
A 69-year-old female was diagnosed with a solid, amelanotic iris mass in her left eye. Differential diagnostics and ancillary tests subsequently led to the diagnosis of disseminated small-cell lung carcinoma. Systemic chemotherapy was indicated after fine needle biopsy verification of metastatic lung cancer. Iris metastasis responded well to the chemotherapy, its regression was observed and secondary open-angle glaucoma was controlled as well. Good visual functions were preserved during the treatment.
Metastatic carcinoma of the iris may be the first sign of disseminated malignant disease. Small-cell lung carcinoma iris metastasis can be treated with chemotherapy. This treatment preserved visual functions, which enhanced the patient's quality of life.</abstract><cop>Czech Republic</cop><pmid>19731881</pmid><tpages>4</tpages></addata></record> |
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| ispartof | Klinická onkologie, 2009, Vol.22 (4), p.179-182 |
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| language | cze |
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| source | MEDLINE; Alma/SFX Local Collection; EZB Electronic Journals Library |
| subjects | Aged Female Humans Iris Neoplasms - secondary Lung Neoplasms - pathology Mediastinal Neoplasms - diagnosis Mediastinal Neoplasms - secondary Small Cell Lung Carcinoma - diagnosis Small Cell Lung Carcinoma - secondary |
| title | Iris metastasis as the first sign of small-cell lung carcinoma with metastatic involvement of the mediastinum |
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