Diagnostics of Single Base-Mismatch DNA Hybridization on Gold Nanoparticles by Using the Hyper-Rayleigh Scattering Technique

Highly sensitive: The hyper‐Rayleigh Scattering (HRS) technique has been used to achieve the ultrasensitive detection of single base‐pair mismatches in oligonucleotide strands without any modification of DNA. A very distinct HRS intensity change is observed after hybridization even at the concentrat...

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Veröffentlicht in:	Angewandte Chemie International Edition 2006-02, Vol.45 (7), p.1151-1154
1. Verfasser:	Ray, Paresh Chandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Base Pair Mismatch base pairs DNA - chemistry DNA structures Gold - chemistry hyper-Rayleigh scattering Microscopy, Electron, Transmission Nanoparticles nanostructures Oligonucleotides - chemical synthesis Oligonucleotides - chemistry Scattering, Radiation Sodium Chloride - chemistry
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