Structural-functional model of the mitotic chromosome

In the present review the structural role of noncoding DNA, mechanisms of differential staining of mitotic chromosomes, and structural organization of different levels of DNA compactization are discussed. A structural-functional model of the mitotic chromosome is proposed based on the principle of d...

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Veröffentlicht in:Biochemistry (Moscow) 2006-01, Vol.71 (1), p.1-9
Hauptverfasser: Polyakov, V Yu, Zatsepina, O V, Kireev, I I, Prusov, A N, Fais, D I, Sheval, E V, Koblyakova, Yu V, Golyshev, S A, Chentsov, Yu S
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container_issue 1
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container_title Biochemistry (Moscow)
container_volume 71
creator Polyakov, V Yu
Zatsepina, O V
Kireev, I I
Prusov, A N
Fais, D I
Sheval, E V
Koblyakova, Yu V
Golyshev, S A
Chentsov, Yu S
description In the present review the structural role of noncoding DNA, mechanisms of differential staining of mitotic chromosomes, and structural organization of different levels of DNA compactization are discussed. A structural-functional model of the mitotic chromosome is proposed based on the principle of discreteness of structural levels of DNA compactization.
doi_str_mv 10.1134/S0006297906010019
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subjects Animals
Calcium - metabolism
Chromatin - chemistry
Chromatin - ultrastructure
Chromosomal Proteins, Non-Histone - chemistry
Chromosomal Proteins, Non-Histone - metabolism
Chromosomes - chemistry
Chromosomes - metabolism
Chromosomes - ultrastructure
Chromosomes, Human - chemistry
Chromosomes, Human - metabolism
Chromosomes, Human - ultrastructure
DNA - chemistry
Euchromatin - chemistry
Euchromatin - metabolism
Heterochromatin - chemistry
Heterochromatin - metabolism
Histones - chemistry
Histones - metabolism
Humans
Interphase
Mitosis
title Structural-functional model of the mitotic chromosome
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