Nup-PI: The Nucleopore-Promoter Interaction of Genes in Yeast

Our previous work identified the inner basket of the NPC as a physical activation/protection station for force-tethered, epigenetically silenced genes. Here we show that a specific nucleopore-to-gene-promoter interaction (Nup-PI) is an early physiological event of gene activation. Nup-PI was discove...

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Veröffentlicht in:	Molecular cell 2006-02, Vol.21 (3), p.379-391
Hauptverfasser:	Schmid, Manfred, Arib, Ghislaine, Laemmli, Caroline, Nishikawa, Junichi, Durussel, Thérèse, Laemmli, Ulrich K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatin - metabolism Chromosomes, Fungal Gene Expression Regulation, Fungal Nuclear Pore - metabolism Nuclear Pore Complex Proteins - genetics Nuclear Pore Complex Proteins - metabolism Oligonucleotide Array Sequence Analysis Promoter Regions, Genetic Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Transcription, Genetic Transcriptional Activation
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