Optimization of chronic stress paradigms using anxiety- and depression-like behavioral parameters

Chronic stress is a risk factor for psychiatric illnesses, such as anxiety and depression disorders. To understand the underlying mechanism regarding how chronic stress triggers such psychiatric dysfunctions, restraint‐based chronic stress models have been attempted in the past. However, total durat...

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Veröffentlicht in:	Journal of neuroscience research 2006-02, Vol.83 (3), p.497-507
Hauptverfasser:	Kim, Kyoung-Shim, Han, Pyung-Lim
Format:	Artikel
Sprache:	eng
Schlagworte:	Amygdala - metabolism Amygdala - physiopathology Analysis of Variance Animals anxiety Anxiety - diagnosis Anxiety - etiology Anxiety - genetics Behavior, Animal - physiology Chronic Disease chronic restraint stress depression Depression - diagnosis Depression - etiology Depression - genetics Disease Models, Animal Gene Expression Gene Expression Regulation Hippocampus - metabolism Hippocampus - physiopathology Male Maze Learning - physiology Mice Mice, Inbred C57BL microarray Oligonucleotide Array Sequence Analysis - methods Restraint, Physical - methods Reverse Transcriptase Polymerase Chain Reaction - methods Risk Assessment Risk Factors RNA, Messenger - metabolism Stress, Physiological - complications Stress, Physiological - genetics Stress, Physiological - pathology Time Factors
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