Sentinel node mapping for gastric cancer
Sentinel lymph node mapping is the standard of care for patients with malignant melanoma and breast cancer. Recently, SLN mapping was introduced to the field of gastric cancer. To evaluate SLN mapping in patients with gastric cancer. In 43 patients with gastric cancer, open intraoperative subserosal...
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Veröffentlicht in: | The Israel Medical Association journal 2006-01, Vol.8 (1), p.40-43 |
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creator | Rabin, Igor Chikman, Bar Halpern, Zvi Wassermann, Ilan Lavy, Ron Gold-Deutch, Ruth Sandbank, Judith Halevy, Ariel |
description | Sentinel lymph node mapping is the standard of care for patients with malignant melanoma and breast cancer. Recently, SLN mapping was introduced to the field of gastric cancer.
To evaluate SLN mapping in patients with gastric cancer.
In 43 patients with gastric cancer, open intraoperative subserosal dye injection in four opposing peritumoral points was used. Ten minutes following dye injection, stained LNs were located, marked and examined postoperatively from the surgical specimen.
SLN mapping was performed in 43 patients with gastric cancer; 782 lymph nodes were harvested and evaluated. SLNs were stained in 34 of the patients (79.1%) with a mean of 2.85 SLNs per patient. The false negative rate was 20.9%, the positive predictive value 100%, the negative predictive value 78.6% and the sensitivity 86.9%.
SLN mapping in patients with gastric cancer is feasible and easy to perform. SLN mapping may mainly affect the extent of lymph node dissection, and to a lesser degree gastric resection. However, more data are needed. |
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To evaluate SLN mapping in patients with gastric cancer.
In 43 patients with gastric cancer, open intraoperative subserosal dye injection in four opposing peritumoral points was used. Ten minutes following dye injection, stained LNs were located, marked and examined postoperatively from the surgical specimen.
SLN mapping was performed in 43 patients with gastric cancer; 782 lymph nodes were harvested and evaluated. SLNs were stained in 34 of the patients (79.1%) with a mean of 2.85 SLNs per patient. The false negative rate was 20.9%, the positive predictive value 100%, the negative predictive value 78.6% and the sensitivity 86.9%.
SLN mapping in patients with gastric cancer is feasible and easy to perform. SLN mapping may mainly affect the extent of lymph node dissection, and to a lesser degree gastric resection. However, more data are needed.</description><identifier>ISSN: 1565-1088</identifier><identifier>PMID: 16450751</identifier><language>eng</language><publisher>Israel</publisher><subject>Adult ; Aged ; Female ; Humans ; Intraoperative Period ; Lymphatic Metastasis ; Male ; Middle Aged ; Sentinel Lymph Node Biopsy - methods ; Stomach Neoplasms - pathology ; Stomach Neoplasms - surgery</subject><ispartof>The Israel Medical Association journal, 2006-01, Vol.8 (1), p.40-43</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16450751$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rabin, Igor</creatorcontrib><creatorcontrib>Chikman, Bar</creatorcontrib><creatorcontrib>Halpern, Zvi</creatorcontrib><creatorcontrib>Wassermann, Ilan</creatorcontrib><creatorcontrib>Lavy, Ron</creatorcontrib><creatorcontrib>Gold-Deutch, Ruth</creatorcontrib><creatorcontrib>Sandbank, Judith</creatorcontrib><creatorcontrib>Halevy, Ariel</creatorcontrib><title>Sentinel node mapping for gastric cancer</title><title>The Israel Medical Association journal</title><addtitle>Isr Med Assoc J</addtitle><description>Sentinel lymph node mapping is the standard of care for patients with malignant melanoma and breast cancer. Recently, SLN mapping was introduced to the field of gastric cancer.
To evaluate SLN mapping in patients with gastric cancer.
In 43 patients with gastric cancer, open intraoperative subserosal dye injection in four opposing peritumoral points was used. Ten minutes following dye injection, stained LNs were located, marked and examined postoperatively from the surgical specimen.
SLN mapping was performed in 43 patients with gastric cancer; 782 lymph nodes were harvested and evaluated. SLNs were stained in 34 of the patients (79.1%) with a mean of 2.85 SLNs per patient. The false negative rate was 20.9%, the positive predictive value 100%, the negative predictive value 78.6% and the sensitivity 86.9%.
SLN mapping in patients with gastric cancer is feasible and easy to perform. SLN mapping may mainly affect the extent of lymph node dissection, and to a lesser degree gastric resection. However, more data are needed.</description><subject>Adult</subject><subject>Aged</subject><subject>Female</subject><subject>Humans</subject><subject>Intraoperative Period</subject><subject>Lymphatic Metastasis</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Sentinel Lymph Node Biopsy - methods</subject><subject>Stomach Neoplasms - pathology</subject><subject>Stomach Neoplasms - surgery</subject><issn>1565-1088</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1z01Lw0AUheFZKLZW_4JkJW4C904zH1lK8aNQcKGuw-TOTYkkk3EmWfjvLVhXZ_Nw4L0Qa1RalQjWrsR1zl8AUimor8QKdaXAKFyLh3cOcx94KMLkuRhdjH04Ft2UiqPLc-qpIBeI04247NyQ-fa8G_H5_PSxey0Pby_73eOhjBLquSTUBIjsK7TaYWuoIye1JdasDDmjWnKEVlpgbyR7aNsOK_Cd01Ybvd2I-7_fmKbvhfPcjH0mHgYXeFpyczISTK1O8O4Ml3Zk38TUjy79NP9t218q6UlZ</recordid><startdate>200601</startdate><enddate>200601</enddate><creator>Rabin, Igor</creator><creator>Chikman, Bar</creator><creator>Halpern, Zvi</creator><creator>Wassermann, Ilan</creator><creator>Lavy, Ron</creator><creator>Gold-Deutch, Ruth</creator><creator>Sandbank, Judith</creator><creator>Halevy, Ariel</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200601</creationdate><title>Sentinel node mapping for gastric cancer</title><author>Rabin, Igor ; Chikman, Bar ; Halpern, Zvi ; Wassermann, Ilan ; Lavy, Ron ; Gold-Deutch, Ruth ; Sandbank, Judith ; Halevy, Ariel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p209t-c16c011ed4186a1b7cfca268ce6e57ca75bcac18280ed72ed0bbf140dfa686763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Female</topic><topic>Humans</topic><topic>Intraoperative Period</topic><topic>Lymphatic Metastasis</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Sentinel Lymph Node Biopsy - methods</topic><topic>Stomach Neoplasms - pathology</topic><topic>Stomach Neoplasms - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rabin, Igor</creatorcontrib><creatorcontrib>Chikman, Bar</creatorcontrib><creatorcontrib>Halpern, Zvi</creatorcontrib><creatorcontrib>Wassermann, Ilan</creatorcontrib><creatorcontrib>Lavy, Ron</creatorcontrib><creatorcontrib>Gold-Deutch, Ruth</creatorcontrib><creatorcontrib>Sandbank, Judith</creatorcontrib><creatorcontrib>Halevy, Ariel</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Israel Medical Association journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rabin, Igor</au><au>Chikman, Bar</au><au>Halpern, Zvi</au><au>Wassermann, Ilan</au><au>Lavy, Ron</au><au>Gold-Deutch, Ruth</au><au>Sandbank, Judith</au><au>Halevy, Ariel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sentinel node mapping for gastric cancer</atitle><jtitle>The Israel Medical Association journal</jtitle><addtitle>Isr Med Assoc J</addtitle><date>2006-01</date><risdate>2006</risdate><volume>8</volume><issue>1</issue><spage>40</spage><epage>43</epage><pages>40-43</pages><issn>1565-1088</issn><abstract>Sentinel lymph node mapping is the standard of care for patients with malignant melanoma and breast cancer. Recently, SLN mapping was introduced to the field of gastric cancer.
To evaluate SLN mapping in patients with gastric cancer.
In 43 patients with gastric cancer, open intraoperative subserosal dye injection in four opposing peritumoral points was used. Ten minutes following dye injection, stained LNs were located, marked and examined postoperatively from the surgical specimen.
SLN mapping was performed in 43 patients with gastric cancer; 782 lymph nodes were harvested and evaluated. SLNs were stained in 34 of the patients (79.1%) with a mean of 2.85 SLNs per patient. The false negative rate was 20.9%, the positive predictive value 100%, the negative predictive value 78.6% and the sensitivity 86.9%.
SLN mapping in patients with gastric cancer is feasible and easy to perform. SLN mapping may mainly affect the extent of lymph node dissection, and to a lesser degree gastric resection. However, more data are needed.</abstract><cop>Israel</cop><pmid>16450751</pmid><tpages>4</tpages></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Adult Aged Female Humans Intraoperative Period Lymphatic Metastasis Male Middle Aged Sentinel Lymph Node Biopsy - methods Stomach Neoplasms - pathology Stomach Neoplasms - surgery |
title | Sentinel node mapping for gastric cancer |
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