Human Embryonic Stem Cells Reprogram Myeloid Precursors Following Cell–Cell Fusion

Here, we examine the ability of undifferentiated human embryonic stem cells (hESCs) to reprogram the nuclei of hESC‐derived myeloid precursors following cell–cell fusion. Using an OP9 coculture system, we produced CD45+ CD33+ myeloperoxidase+ myeloid precursors from an Oct4–enhanced green fluorescen...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2006-01, Vol.24 (1), p.168-176
Hauptverfasser:	Yu, Junying, Vodyanik, Maxim A., He, Ping, Slukvin, Igor I., Thomson, James A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Culture Techniques - methods Cell Differentiation Cell fusion Cell Fusion - methods Cell Line Coculture Techniques Human embryonic stem cells Humans Hyaluronan Receptors - metabolism Hybrid cells Hybrid Cells - physiology Mice Mice, Transgenic Myeloid precursors Myeloid Progenitor Cells - physiology Octamer Transcription Factor-3 - genetics Peroxidase - metabolism Pluripotent Stem Cells - physiology Reprogramming Stem Cells
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