Monozygotic twins in infertile patients with advanced maternal age: case reports and review of the literature
Objective To report two cases of successful monozygotic twin pregnancies in women undergoing infertility treatment and to review possible etiologic factors. Design Case report and review of the literature. Setting University of Toronto–affiliated infertility clinic. Patient(s) A 43-year-old woman an...
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| Veröffentlicht in: | Fertility and sterility 2009-09, Vol.92 (3), p.1168.e9-1168.e12 |
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| container_title | Fertility and sterility |
| container_volume | 92 |
| creator | Esfandiari, Navid, D.V.M., Ph.D., H.C.L.D Kapoor, Monica, M.D Burjaq, Hasan, B.Sc., M.T Chang, Paul, M.D Gotlieb, Lynda, R.N Casper, Robert F., M.D |
| description | Objective To report two cases of successful monozygotic twin pregnancies in women undergoing infertility treatment and to review possible etiologic factors. Design Case report and review of the literature. Setting University of Toronto–affiliated infertility clinic. Patient(s) A 43-year-old woman and a 44-year-old woman with history of secondary infertility. Intervention(s) In vitro fertilization and ET. Main Outcome Measure(s) Monozygotic twin pregnancy. Result(s) Delivery of two sets of monozygotic twins. Conclusion(s) The only identified potential risk factors for monozygotic twins are maternal age and assisted reproductive technologies. Both patients reported here were aged >40 years and underwent assisted reproduction procedures, including high-dose gonadotropin stimulation, embryo culture, and, in case 2, intracytoplasmic sperm injection plus assisted hatching. |
| doi_str_mv | 10.1016/j.fertnstert.2009.05.085 |
| format | Article |
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Design Case report and review of the literature. Setting University of Toronto–affiliated infertility clinic. Patient(s) A 43-year-old woman and a 44-year-old woman with history of secondary infertility. Intervention(s) In vitro fertilization and ET. Main Outcome Measure(s) Monozygotic twin pregnancy. Result(s) Delivery of two sets of monozygotic twins. Conclusion(s) The only identified potential risk factors for monozygotic twins are maternal age and assisted reproductive technologies. Both patients reported here were aged >40 years and underwent assisted reproduction procedures, including high-dose gonadotropin stimulation, embryo culture, and, in case 2, intracytoplasmic sperm injection plus assisted hatching.</description><identifier>ISSN: 0015-0282</identifier><identifier>EISSN: 1556-5653</identifier><identifier>DOI: 10.1016/j.fertnstert.2009.05.085</identifier><identifier>PMID: 19608163</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Female ; Humans ; Infertility, Female - therapy ; Internal Medicine ; IVF ; Maternal Age ; Monozygotic twinning ; Obstetrics and Gynecology ; Pregnancy ; Pregnancy Outcome ; Reproductive Techniques, Assisted ; Risk Factors ; Twins, Monozygotic</subject><ispartof>Fertility and sterility, 2009-09, Vol.92 (3), p.1168.e9-1168.e12</ispartof><rights>American Society for Reproductive Medicine</rights><rights>2009 American Society for Reproductive Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c477t-5d330be2a8f5355f8f8b6a2722fd3064de993271e1339548cea38811b44b39b23</citedby><cites>FETCH-LOGICAL-c477t-5d330be2a8f5355f8f8b6a2722fd3064de993271e1339548cea38811b44b39b23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.fertnstert.2009.05.085$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19608163$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Esfandiari, Navid, D.V.M., Ph.D., H.C.L.D</creatorcontrib><creatorcontrib>Kapoor, Monica, M.D</creatorcontrib><creatorcontrib>Burjaq, Hasan, B.Sc., M.T</creatorcontrib><creatorcontrib>Chang, Paul, M.D</creatorcontrib><creatorcontrib>Gotlieb, Lynda, R.N</creatorcontrib><creatorcontrib>Casper, Robert F., M.D</creatorcontrib><title>Monozygotic twins in infertile patients with advanced maternal age: case reports and review of the literature</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>Objective To report two cases of successful monozygotic twin pregnancies in women undergoing infertility treatment and to review possible etiologic factors. Design Case report and review of the literature. Setting University of Toronto–affiliated infertility clinic. Patient(s) A 43-year-old woman and a 44-year-old woman with history of secondary infertility. Intervention(s) In vitro fertilization and ET. Main Outcome Measure(s) Monozygotic twin pregnancy. Result(s) Delivery of two sets of monozygotic twins. Conclusion(s) The only identified potential risk factors for monozygotic twins are maternal age and assisted reproductive technologies. 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| ispartof | Fertility and sterility, 2009-09, Vol.92 (3), p.1168.e9-1168.e12 |
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| source | MEDLINE; Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Adult Female Humans Infertility, Female - therapy Internal Medicine IVF Maternal Age Monozygotic twinning Obstetrics and Gynecology Pregnancy Pregnancy Outcome Reproductive Techniques, Assisted Risk Factors Twins, Monozygotic |
| title | Monozygotic twins in infertile patients with advanced maternal age: case reports and review of the literature |
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