Development of a New HPLC Method for the Simultaneous Determination of Ticarcillin and Clavulanic Acid in Pharmaceutical Formulations

A new HPLC method has been developed and validated for the simultaneous determination of ticarcillin (TIC) and clavulanic acid (CA) in pharmaceutical formulations. The HPLC separation was achieved on a beta-cyclodextrin column (Cyclobond I, 250 x 4.6 mm, 5 microm) with methanol-16 mM pH 6.0 ammonium...

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Veröffentlicht in:	Journal of AOAC International 2009-07, Vol.92 (4), p.1089-1094
Hauptverfasser:	TSOU, Tai-Li, LEE, Chiu-Wey, WANG, Hsian-Jenn, CHENG, Ya-Chung, LIU, Yu-Tien, CHEN, Su-Hwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - analysis Biological and medical sciences Calibration Chemical properties Chemistry, Pharmaceutical Chromatography, High Pressure Liquid Clavulanic Acid - analysis Drug Combinations Drug Stability Enzyme Inhibitors - analysis Food industries Fundamental and applied biological sciences. Psychology High performance liquid chromatography Hot Temperature Identification and classification Indicators and Reagents Methods Penicillin Pharmaceutical Solutions Reference Standards Reproducibility of Results Separation (Technology) Ticarcillin - analysis Ultraviolet Rays
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