A quantitative resazurin assay to determinate the viability of Trichomonas vaginalis and the cytotoxicity of organic solvents and surfactant agents

Trichomonas vaginalis causes trichomonosis, the most common, non-viral sexually transmitted disease. To test anti- Trichomonas agents, usually many with low water solubility, organic solvents and surfactant agents should be used. Therefore, the minimal inhibitory concentration (MIC) of acetone, meth...

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Veröffentlicht in:	Experimental parasitology 2009-10, Vol.123 (2), p.195-198
Hauptverfasser:	Duarte, Mariana, Giordani, Raquel Brandt, De Carli, Geraldo Attilio, Zuanazzi, José Angelo, Macedo, Alexandre José, Tasca, Tiana
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Propanol - pharmacology Acetone - pharmacology Animals Biological and medical sciences Dimethyl Sulfoxide - pharmacology Ethanol - pharmacology Fluorimetric assay Fluorometry Fundamental and applied biological sciences. Psychology Indicators and Reagents - metabolism Life cycle. Host-agent relationship. Pathogenesis Methanol - pharmacology Octoxynol - pharmacology Organic solvents Oxazines - metabolism Parasitic Sensitivity Tests Polysorbates - pharmacology Protozoa Resazurin Solvents - pharmacology Surface-Active Agents - pharmacology Surfactant agents Trichomonas vaginalis Trichomonas vaginalis - drug effects Trichomonas vaginalis - growth & development Trichomonas vaginalis - metabolism Vehicles Xanthenes - metabolism
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