Differential effect of α-syntrophin knockout on aquaporin-4 and Kir4.1 expression in retinal macroglial cells in mice

Aquaporin-4 water channels and the inwardly rectifying potassium channels Kir4.1 are coexpressed in a highly polarized manner at the perivascular and subvitreal endfeet of retinal Müller cells and astrocytes. The present study was aimed at resolving the anchoring mechanisms responsible for the coexp...

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Veröffentlicht in:	Neuroscience 2006, Vol.137 (1), p.165-175
Hauptverfasser:	Puwarawuttipanit, W., Bragg, A.D., Frydenlund, D.S., Mylonakou, M.-N., Nagelhus, E.A., Peters, M.F., Kotchabhakdi, N., Adams, M.E., Froehner, S.C., Haug, F.-M., Ottersen, O.P., Amiry-Moghaddam, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aquaporin 4 - biosynthesis Biological and medical sciences Calcium-Binding Proteins - deficiency Calcium-Binding Proteins - genetics Cell Polarity - genetics dystrophin Eye and associated structures. Visual pathways and centers. Vision Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology Image Processing, Computer-Assisted Immunohistochemistry inwardly rectifying potassium channels Male Membrane Proteins - deficiency Membrane Proteins - genetics Mice Mice, Knockout Microscopy, Confocal Muscle Proteins - deficiency Muscle Proteins - genetics Müller cells Neuroglia - metabolism Potassium Channels, Inwardly Rectifying - biosynthesis Retina - cytology Retina - metabolism syntrophins Vertebrates: nervous system and sense organs water channels
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