Tubulin nitration in human gliomas

Immunohistochemical and biochemical investigations showed that significant protein nitration occurs in human gliomas, especially in grade IV glioblastomas at the level of astrocytes and oligodendrocytes and neurones. Enhanced alpha-tubulin immunoreactivity was co-present in the same elements in the...

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Veröffentlicht in:	Neuroscience letters 2006-02, Vol.394 (1), p.57-62
Hauptverfasser:	Fiore, Gabriella, Cristo, Carlo Di, Monti, Gianluca, Amoresano, Angela, Columbano, Laura, Pucci, Pietro, Cioffi, Fernando A., Cosmo, Anna Di, Palumbo, Anna, d’Ischia, Marco
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Astrocytes - metabolism Biological and medical sciences Blotting, Western - methods Brain Neoplasms - metabolism Chromatography, High Pressure Liquid - methods Female Fundamental and applied biological sciences. Psychology Glioma - metabolism Glioma - pathology Gliomas Humans Immunohistochemistry Immunohistochemistry - methods Isolated neuron and nerve. Neuroglia Male Middle Aged Neurons - metabolism Nitrotyrosine Proteomics Proteomics - methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Tubulin Tubulin - metabolism Tyrosine - analogs & derivatives Tyrosine - metabolism Vertebrates: nervous system and sense organs
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