Histone lysine methylation patterns in human cell types are arranged in distinct three-dimensional nuclear zones

The impact of histone lysine methylation as an essential epigenetic mechanism for gene regulation has been demonstrated by numerous studies where it was functionally and structurally linked to euchromatin and heterochromatin. Most of these data have been obtained by biochemical and two-dimensional (...

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Veröffentlicht in:	Histochemistry and cell biology 2006-01, Vol.125 (1-2), p.3-19
Hauptverfasser:	Zinner, Roman, Albiez, Heiner, Walter, Joachim, Peters, Antoine H F M, Cremer, Thomas, Cremer, Marion
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Cell Cycle - physiology Cell Nucleus - metabolism Cell Nucleus - ultrastructure Cells, Cultured Centromere - metabolism Centromere - ultrastructure DNA - biosynthesis DNA - metabolism Female Fibroblasts - metabolism Fibroblasts - ultrastructure Histones - metabolism Humans Image Processing, Computer-Assisted Immunohistochemistry Lysine - metabolism Methylation Microscopy, Confocal RNA - biosynthesis RNA - metabolism
Online-Zugang:	Volltext
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