Transient Osmotic Absorption of Fluid in Microvessels Exposed to Low Concentrations of Dimethyl Sulfoxide

Dimethyl Sulfoxide (DMSO) is a common solvent for pharmacological agents. It is a small, lipophilic molecule thought to be relatively highly permeable through the cell membrane. While measuring the effect of low concentrations of DMSO (0.05-0.5% v/v) on capillary hydraulic conductivity as a vehicle...

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Veröffentlicht in:	Microcirculation (New York, N.Y. 1994) N.Y. 1994), 2006-01, Vol.13 (1), p.29-40
Hauptverfasser:	GLASS, CATHERINE A., PERRIN, RACHEL M., POCOCK, TRISTAN M., BATES, DAVID O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Animals Capillaries Capillary Permeability - drug effects Cryoprotective Agents - pharmacology Dimethyl Sulfoxide - pharmacology DMSO Dose-Response Relationship, Drug hydraulic conductivity Male Microcirculation - drug effects Osmosis Osmotic Pressure - drug effects Rana temporaria Rats Rats, Wistar reflection coefficient vascular permeability
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