Histone methyltransferase PRDM8 regulates mouse testis steroidogenesis

A family of PRDM proteins are similar to histone methyltransferases (HMTases) with SET domain in that they modulate different cellular processes, including transcriptional regulation, through chromatin modifying activities. By applying a bioinformatic approach, we searched for proteins containing th...

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Veröffentlicht in:	Biochemical and biophysical research communications 2009-10, Vol.388 (1), p.131-136
Hauptverfasser:	Eom, Gwang Hyeon, Kim, Kabsun, Kim, Sung-Mi, Kee, Hae Jin, Kim, Ji-Young, Jin, Hye Mi, Kim, Ju-Ryoung, Kim, Jung Ha, Choe, Nakwon, Kim, Kee-Beom, Lee, Junwon, Kook, Hyun, Kim, Nacksung, Seo, Sang-Beom
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cloning, Molecular Computational Biology Gene Expression Regulation Gonadal Steroid Hormones - biosynthesis Histone Histone Methyltransferases Histone-Lysine N-Methyltransferase - chemistry Histone-Lysine N-Methyltransferase - genetics Histone-Lysine N-Methyltransferase - metabolism Male Methyltransferase Mice PRDM8 Repressor Proteins - chemistry Repressor Proteins - genetics Repressor Proteins - metabolism Steroidogenesis Testis - enzymology Testis - growth & development Tissue Distribution Transcription Transcription, Genetic Zinc Fingers
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