Survival Effects of Postmastectomy Adjuvant Radiation Therapy Using Biologically Equivalent Doses: A Clinical Perspective

Background: Postmastectomy radiation therapy reduces locoregional recurrence among women with operable breast cancer, but whether it improves survival has been controversial. We reanalyzed the results from 36 unconfounded trials (i.e., addition of radiation therapy was the sole discriminant between...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2006-01, Vol.98 (1), p.26-38
Hauptverfasser:	Gebski, Val, Lagleva, Marivic, Keech, Anthony, Simes, John, Langlands, Allan O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Breast cancer Breast Neoplasms - mortality Breast Neoplasms - pathology Breast Neoplasms - radiotherapy Breast Neoplasms - surgery Confidence Intervals Disease-Free Survival Female Genital system. Mammary gland Humans Mastectomy Medical sciences Multicenter Studies as Topic Neoplasm Recurrence, Local - prevention & control Neoplasm Staging Odds Ratio Radiation Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted Radiotherapy, Adjuvant - methods Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Randomized Controlled Trials as Topic Survival Analysis Therapeutic Equivalency Time Factors Treatment Outcome Tumors
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