Analysis of regional left ventricular function by cineventriculography, cardiac magnetic resonance imaging, and unenhanced and contrast-enhanced echocardiography: a multicenter comparison of methods
To define the use of cineventriculography, cardiac magnetic resonance imaging (cMRI), and unenhanced and contrast-enhanced echocardiography for detection of left ventricular (LV) regional wall motion abnormalities (RWMA). Detection of RWMA is integral to the evaluation of LV function. In 100 patient...
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| Veröffentlicht in: | Journal of the American College of Cardiology 2006-01, Vol.47 (1), p.121-128 |
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| creator | Hoffmann, Rainer von Bardeleben, Stephan Kasprzak, Jaroslaw D Borges, Adrian C ten Cate, Folkert Firschke, Christian Lafitte, Stephane Al-Saadi, Nidal Kuntz-Hehner, Stefanie Horstick, Georg Greis, Christian Engelhardt, Marc Vanoverschelde, Jean Louis Becher, Harald |
| description | To define the use of cineventriculography, cardiac magnetic resonance imaging (cMRI), and unenhanced and contrast-enhanced echocardiography for detection of left ventricular (LV) regional wall motion abnormalities (RWMA).
Detection of RWMA is integral to the evaluation of LV function.
In 100 patients, cineventriculography and unenhanced and contrast-enhanced echocardiography were performed. Fifty-six of the patients underwent additional cMRI. RWMA were assessed referring to a 16-segment model for cMRI, unenhanced and contrast echocardiography. Cineventriculography was evaluated on a 7-segment model. Hypokinesia in one or more segments defined presence of RWMA. Interobserver agreement among three readers was determined within each imaging modality. Intermethod agreement between imaging modalities was analyzed. A standard of truth for the presence of RWMA was obtained by an independent expert panel decision (EPD) based on clinical data, electrocardiogram, coronary angiography, and blinded information from the imaging modalities.
Sixty-seven patients were found to have an RWMA by EPD. Interobserver agreement expressed as kappa coefficient was 0.41 (range 0.37 to 0.44) for unenhanced echocardiography, 0.43 (range 0.29 to 0.79) for cMRT, 0.56 (range 0.44 to 0.70) for cineventriculography, and 0.77 (range 0.71 to 0.88) for contrast echocardiography. Contrast enhancement compared to unenhanced echocardiography improved agreement of echocardiography related to cMRI (kappa 0.46 vs. 0.29) and related to cineventriculography (kappa 0.59 vs. 0.28). Accuracy to detect EPD-defined RWMA was highest for contrast echocardiography, followed by cMRI, unenhanced echocardiography, and cineventriculography.
Analysis of RWMA is characterized by considerable interobserver variability even using high-quality imaging modalities. Interobserver agreement on RWMA and accuracy to detect panel-defined RWMA is good using contrast echocardiography. |
| doi_str_mv | 10.1016/j.jacc.2005.10.012 |
| format | Article |
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Detection of RWMA is integral to the evaluation of LV function.
In 100 patients, cineventriculography and unenhanced and contrast-enhanced echocardiography were performed. Fifty-six of the patients underwent additional cMRI. RWMA were assessed referring to a 16-segment model for cMRI, unenhanced and contrast echocardiography. Cineventriculography was evaluated on a 7-segment model. Hypokinesia in one or more segments defined presence of RWMA. Interobserver agreement among three readers was determined within each imaging modality. Intermethod agreement between imaging modalities was analyzed. A standard of truth for the presence of RWMA was obtained by an independent expert panel decision (EPD) based on clinical data, electrocardiogram, coronary angiography, and blinded information from the imaging modalities.
Sixty-seven patients were found to have an RWMA by EPD. Interobserver agreement expressed as kappa coefficient was 0.41 (range 0.37 to 0.44) for unenhanced echocardiography, 0.43 (range 0.29 to 0.79) for cMRT, 0.56 (range 0.44 to 0.70) for cineventriculography, and 0.77 (range 0.71 to 0.88) for contrast echocardiography. Contrast enhancement compared to unenhanced echocardiography improved agreement of echocardiography related to cMRI (kappa 0.46 vs. 0.29) and related to cineventriculography (kappa 0.59 vs. 0.28). Accuracy to detect EPD-defined RWMA was highest for contrast echocardiography, followed by cMRI, unenhanced echocardiography, and cineventriculography.
Analysis of RWMA is characterized by considerable interobserver variability even using high-quality imaging modalities. Interobserver agreement on RWMA and accuracy to detect panel-defined RWMA is good using contrast echocardiography.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2005.10.012</identifier><identifier>PMID: 16386674</identifier><language>eng</language><publisher>United States: Elsevier Limited</publisher><subject>Cardiology ; Cineradiography ; Contrast Media ; Coronary vessels ; Echocardiography ; Electrocardiography ; Female ; Heart ; Heart attacks ; Heart Ventricles - diagnostic imaging ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Myocardial Contraction ; NMR ; Nuclear magnetic resonance ; Observer Variation ; Older people ; Phospholipids ; Sensitivity and Specificity ; Sulfur Hexafluoride ; Ventricular Dysfunction, Left - diagnosis ; Ventricular Function, Left</subject><ispartof>Journal of the American College of Cardiology, 2006-01, Vol.47 (1), p.121-128</ispartof><rights>Copyright Elsevier Limited Jan 3, 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16386674$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hoffmann, Rainer</creatorcontrib><creatorcontrib>von Bardeleben, Stephan</creatorcontrib><creatorcontrib>Kasprzak, Jaroslaw D</creatorcontrib><creatorcontrib>Borges, Adrian C</creatorcontrib><creatorcontrib>ten Cate, Folkert</creatorcontrib><creatorcontrib>Firschke, Christian</creatorcontrib><creatorcontrib>Lafitte, Stephane</creatorcontrib><creatorcontrib>Al-Saadi, Nidal</creatorcontrib><creatorcontrib>Kuntz-Hehner, Stefanie</creatorcontrib><creatorcontrib>Horstick, Georg</creatorcontrib><creatorcontrib>Greis, Christian</creatorcontrib><creatorcontrib>Engelhardt, Marc</creatorcontrib><creatorcontrib>Vanoverschelde, Jean Louis</creatorcontrib><creatorcontrib>Becher, Harald</creatorcontrib><title>Analysis of regional left ventricular function by cineventriculography, cardiac magnetic resonance imaging, and unenhanced and contrast-enhanced echocardiography: a multicenter comparison of methods</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>To define the use of cineventriculography, cardiac magnetic resonance imaging (cMRI), and unenhanced and contrast-enhanced echocardiography for detection of left ventricular (LV) regional wall motion abnormalities (RWMA).
Detection of RWMA is integral to the evaluation of LV function.
In 100 patients, cineventriculography and unenhanced and contrast-enhanced echocardiography were performed. Fifty-six of the patients underwent additional cMRI. RWMA were assessed referring to a 16-segment model for cMRI, unenhanced and contrast echocardiography. Cineventriculography was evaluated on a 7-segment model. Hypokinesia in one or more segments defined presence of RWMA. Interobserver agreement among three readers was determined within each imaging modality. Intermethod agreement between imaging modalities was analyzed. A standard of truth for the presence of RWMA was obtained by an independent expert panel decision (EPD) based on clinical data, electrocardiogram, coronary angiography, and blinded information from the imaging modalities.
Sixty-seven patients were found to have an RWMA by EPD. Interobserver agreement expressed as kappa coefficient was 0.41 (range 0.37 to 0.44) for unenhanced echocardiography, 0.43 (range 0.29 to 0.79) for cMRT, 0.56 (range 0.44 to 0.70) for cineventriculography, and 0.77 (range 0.71 to 0.88) for contrast echocardiography. Contrast enhancement compared to unenhanced echocardiography improved agreement of echocardiography related to cMRI (kappa 0.46 vs. 0.29) and related to cineventriculography (kappa 0.59 vs. 0.28). Accuracy to detect EPD-defined RWMA was highest for contrast echocardiography, followed by cMRI, unenhanced echocardiography, and cineventriculography.
Analysis of RWMA is characterized by considerable interobserver variability even using high-quality imaging modalities. Interobserver agreement on RWMA and accuracy to detect panel-defined RWMA is good using contrast echocardiography.</description><subject>Cardiology</subject><subject>Cineradiography</subject><subject>Contrast Media</subject><subject>Coronary vessels</subject><subject>Echocardiography</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Heart</subject><subject>Heart attacks</subject><subject>Heart Ventricles - diagnostic imaging</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial Contraction</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Observer Variation</subject><subject>Older people</subject><subject>Phospholipids</subject><subject>Sensitivity and Specificity</subject><subject>Sulfur Hexafluoride</subject><subject>Ventricular Dysfunction, Left - diagnosis</subject><subject>Ventricular Function, Left</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkc-O1DAMxiMEYoeFF-CAIiFx2g5xMk1abqsV_6SVuMC5clNnmlGbDEmLNC_Ic5FZhj1wsvz588-WzdhrEFsQoN8ftge0diuFqIuwFSCfsA3UdVOpujVP2UYYVVcgWnPFXuR8EELoBtrn7Aq0arQ2uw37fRtwOmWfeXQ80d7HkvOJ3MJ_UViSt-uEibs12KXUeH_i1gd6rMV9wuN4uuEW0-DR8hn3gRZvCywXVrDEfdF82N9wDANfA4XxLA8PqY0FhHmpHlWyY3yAXdAfOPJ5nQqyzKRUOuYjJl_g55VnWsY45JfsmcMp06tLvGY_Pn38fveluv_2-evd7X01SgNL1WNf76Sk1hE5Y1XjpGpsAwC6R20c2YHszgiN1KBuJaCy1KNTBFK2CtQ1e_eXe0zx50p56WafLU0TBopr7rTRQkF9Nr79z3iIayq3zR3UQoPWTauK683FtfYzDd0xlVulU_fvP-oPwuuZ5g</recordid><startdate>20060103</startdate><enddate>20060103</enddate><creator>Hoffmann, Rainer</creator><creator>von Bardeleben, Stephan</creator><creator>Kasprzak, Jaroslaw D</creator><creator>Borges, Adrian C</creator><creator>ten Cate, Folkert</creator><creator>Firschke, Christian</creator><creator>Lafitte, Stephane</creator><creator>Al-Saadi, Nidal</creator><creator>Kuntz-Hehner, Stefanie</creator><creator>Horstick, Georg</creator><creator>Greis, Christian</creator><creator>Engelhardt, Marc</creator><creator>Vanoverschelde, Jean Louis</creator><creator>Becher, Harald</creator><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20060103</creationdate><title>Analysis of regional left ventricular function by cineventriculography, cardiac magnetic resonance imaging, and unenhanced and contrast-enhanced echocardiography: a multicenter comparison of methods</title><author>Hoffmann, Rainer ; 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Detection of RWMA is integral to the evaluation of LV function.
In 100 patients, cineventriculography and unenhanced and contrast-enhanced echocardiography were performed. Fifty-six of the patients underwent additional cMRI. RWMA were assessed referring to a 16-segment model for cMRI, unenhanced and contrast echocardiography. Cineventriculography was evaluated on a 7-segment model. Hypokinesia in one or more segments defined presence of RWMA. Interobserver agreement among three readers was determined within each imaging modality. Intermethod agreement between imaging modalities was analyzed. A standard of truth for the presence of RWMA was obtained by an independent expert panel decision (EPD) based on clinical data, electrocardiogram, coronary angiography, and blinded information from the imaging modalities.
Sixty-seven patients were found to have an RWMA by EPD. Interobserver agreement expressed as kappa coefficient was 0.41 (range 0.37 to 0.44) for unenhanced echocardiography, 0.43 (range 0.29 to 0.79) for cMRT, 0.56 (range 0.44 to 0.70) for cineventriculography, and 0.77 (range 0.71 to 0.88) for contrast echocardiography. Contrast enhancement compared to unenhanced echocardiography improved agreement of echocardiography related to cMRI (kappa 0.46 vs. 0.29) and related to cineventriculography (kappa 0.59 vs. 0.28). Accuracy to detect EPD-defined RWMA was highest for contrast echocardiography, followed by cMRI, unenhanced echocardiography, and cineventriculography.
Analysis of RWMA is characterized by considerable interobserver variability even using high-quality imaging modalities. Interobserver agreement on RWMA and accuracy to detect panel-defined RWMA is good using contrast echocardiography.</abstract><cop>United States</cop><pub>Elsevier Limited</pub><pmid>16386674</pmid><doi>10.1016/j.jacc.2005.10.012</doi><tpages>8</tpages></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Cardiology Cineradiography Contrast Media Coronary vessels Echocardiography Electrocardiography Female Heart Heart attacks Heart Ventricles - diagnostic imaging Humans Magnetic Resonance Imaging Male Middle Aged Myocardial Contraction NMR Nuclear magnetic resonance Observer Variation Older people Phospholipids Sensitivity and Specificity Sulfur Hexafluoride Ventricular Dysfunction, Left - diagnosis Ventricular Function, Left |
| title | Analysis of regional left ventricular function by cineventriculography, cardiac magnetic resonance imaging, and unenhanced and contrast-enhanced echocardiography: a multicenter comparison of methods |
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