Risk of Hepatocellular Carcinoma Across a Biological Gradient of Serum Hepatitis B Virus DNA Level

CONTEXT Serum hepatitis B virus (HBV) DNA level is a marker of viral replication and efficacy of antiviral treatment in individuals with chronic hepatitis B. OBJECTIVE To evaluate the relationship between serum HBV DNA level and risk of hepatocellular carcinoma. DESIGN, SETTING, AND PARTICIPANTS Pro...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2006-01, Vol.295 (1), p.65-73
Hauptverfasser:	Chen, Chien-Jen, Yang, Hwai-I, Su, Jun, Jen, Chin-Lan, You, San-Lin, Lu, Sheng-Nan, Huang, Guan-Tarn, Iloeje, Uchenna H, REVEAL-HBV Study Group, for the
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alanine Transaminase - blood Biological and medical sciences Cancer Carcinoma, Hepatocellular - epidemiology Carcinoma, Hepatocellular - virology Deoxyribonucleic acid DNA DNA, Viral - blood Female Gastroenterology. Liver. Pancreas. Abdomen General aspects Health risk assessment Hepatitis Hepatitis B e Antigens - blood Hepatitis B virus Hepatitis B virus - isolation & purification Hepatitis B virus - pathogenicity Hepatitis B, Chronic - physiopathology Hepatitis C virus Human viral diseases Humans Incidence Infectious diseases Liver Cirrhosis Liver Neoplasms - epidemiology Liver Neoplasms - virology Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Middle Aged Proportional Hazards Models Prospective Studies Risk Factors Taiwan Tumors Viral diseases Viral hepatitis Viruses
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