Application of Proteomic Technology in Identifying Pancreatic Secretory Trypsin Inhibitor Variants in Urine of Patients with Pancreatitis

Although the analysis of genetic variability has traditionally been performed with molecular genetic techniques, the development of proteomic technology has raised the possibility of analyzing genetic variants at the protein level. This method provides additional information about posttranslational...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2006-01, Vol.52 (1), p.73-81
Hauptverfasser:	Valmu, Leena, Paju, Annukka, Lempinen, Marko, Kemppainen, Esko, Stenman, Ulf-Hakan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Amino Acid Sequence Amino acids Analytical, structural and metabolic biochemistry Biological and medical sciences Carrier Proteins - genetics Carrier Proteins - urine Disease Enzymes Female Fundamental and applied biological sciences. Psychology Genetic variance Humans Investigative techniques, diagnostic techniques (general aspects) Ionization Male Mass spectrometry Medical sciences Middle Aged Molecular Sequence Data Mutation Pancreatitis Pancreatitis, Chronic - genetics Pancreatitis, Chronic - urine Patients Proteinase inhibitors Proteins Proteomics Scientific imaging Sensitivity and Specificity Spectrometry, Mass, Electrospray Ionization Trypsin Inhibitor, Kazal Pancreatic Urine
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