Expression of the Decay-Accelerating Factor (CD55) in Renal Transplants-A Possible Prediction Marker of Allograft Survival

Decay-accelerating factor (CD55) accelerates the decay of C3 and C5 convertases, participating in classical and alternative complement activation pathways. Complement activation plays a major role in antibody-mediated rejection of allografts (AMR); C4d is used as a marker of AMR. Emerging evidence s...

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Veröffentlicht in:	Transplantation 2009-08, Vol.88 (4), p.457-464
Hauptverfasser:	BRODSKY, Sergey V, NADASDY, Gyongyi M, PELLETIER, Ronald, SATOSKAR, Anjali, BIRMINGHAM, Daniel J, HADLEY, GreggA, OBEIDAT, Khaled, NADASDY, Tibor
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Biomarkers - metabolism Capillaries - immunology CD55 Antigens - metabolism Complement C4b - metabolism Complement Pathway, Alternative Female Fundamental and applied biological sciences. Psychology Fundamental immunology Graft Survival - immunology Humans Immunohistochemistry Isoantibodies - metabolism Kaplan-Meier Estimate Kidney - blood supply Kidney - immunology Kidney - pathology Kidney Transplantation - immunology Kidney Transplantation - pathology Male Medical sciences Middle Aged Peptide Fragments - metabolism Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue, organ and graft immunology Transplantation, Homologous
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