Distinct Orbitofrontal Regions Encode Stimulus and Choice Valuation
The weak axiom of revealed preferences suggests that the value of an object can be understood through the simple examination of choices. Although this axiom has driven economic theory, the assumption of equation between value and choice is often violated. fMRI was used to decouple the processes asso...
Gespeichert in:
| Veröffentlicht in: | Journal of cognitive neuroscience 2009-10, Vol.21 (10), p.1956-1966 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1966 |
|---|---|
| container_issue | 10 |
| container_start_page | 1956 |
| container_title | Journal of cognitive neuroscience |
| container_volume | 21 |
| creator | Cunningham, William A. Kesek, Amanda Mowrer, Samantha M. |
| description | The weak axiom of revealed preferences suggests that the value of an object can be understood through the simple examination of choices. Although this axiom has driven economic theory, the assumption of equation between value and choice is often violated. fMRI was used to decouple the processes associated with evaluating stimuli from evaluating one's actions. Whereas activity in left posterior areas of the orbitofrontal cortex (OFC) was associated with processing the objective value of stimuli, activity in medial anterior areas of the OFC was associated with accepting high value gambles and rejecting low value gambles; that is, making correct decisions. These data demonstrate that distinct areas of the OFC provide dissociated representations for use in adaptive decision-making and suggest an important processing distinction between the concepts of good/bad and right/wrong. |
| doi_str_mv | 10.1162/jocn.2008.21148 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_mit_j</sourceid><recordid>TN_cdi_proquest_miscellaneous_67596167</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ericid>EJ864657</ericid><sourcerecordid>20967415</sourcerecordid><originalsourceid>FETCH-LOGICAL-c471t-54938f02f78ed374e1e54a2cde795075031ce1df931cf44aa9b090bf28d81cc03</originalsourceid><addsrcrecordid>eNqFkcFP2zAUxq0JNLqy8y4IRTvsMqU8O7ZjH6e2GyAkpAHTbpbrOOAqiYudTNr-epy1YhMCcfoO7-f3fX4fQh8wzDDm5GTtTTcjAGJGMKbiDZpgVkAuhBR7aAJJcknkzwP0LsY1ABDG6Vt0gIVgjFE6QfOFi73rTJ9dhpXrfR181-sm-25vne9ituyMr2x21bt2aIaY6a7K5nfeGZv90M2g-0Qdov1aN9G-3-kU3XxdXs9P84vLb2fzLxe5oSXuc0ZlIWogdSlsVZTUYsuoJqaypWRQMiiwsbiqZdKaUq3lCiSsaiIqgY2BYoo-bfdugr8fbOxV66KxTaM764eoeMkkx7x8FSQgeUnTpabo4xNw7YfQpU8oQgpgKRRP0MkWMsHHGGytNsG1OvxWGNTYghpbUGML6m8L6cXxbu2wam31j9-dPQFHW8AGZx7Hy3PBKWdj_sV23Lr_Eo0uvwh2ybUAQhgkS4JTApWM_7jNMzE-P7PmpdAPsdaucQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>223057506</pqid></control><display><type>article</type><title>Distinct Orbitofrontal Regions Encode Stimulus and Choice Valuation</title><source>MEDLINE</source><source>MIT Press Journals</source><creator>Cunningham, William A. ; Kesek, Amanda ; Mowrer, Samantha M.</creator><creatorcontrib>Cunningham, William A. ; Kesek, Amanda ; Mowrer, Samantha M.</creatorcontrib><description>The weak axiom of revealed preferences suggests that the value of an object can be understood through the simple examination of choices. Although this axiom has driven economic theory, the assumption of equation between value and choice is often violated. fMRI was used to decouple the processes associated with evaluating stimuli from evaluating one's actions. Whereas activity in left posterior areas of the orbitofrontal cortex (OFC) was associated with processing the objective value of stimuli, activity in medial anterior areas of the OFC was associated with accepting high value gambles and rejecting low value gambles; that is, making correct decisions. These data demonstrate that distinct areas of the OFC provide dissociated representations for use in adaptive decision-making and suggest an important processing distinction between the concepts of good/bad and right/wrong.</description><identifier>ISSN: 0898-929X</identifier><identifier>EISSN: 1530-8898</identifier><identifier>DOI: 10.1162/jocn.2008.21148</identifier><identifier>PMID: 18855544</identifier><language>eng</language><publisher>One Rogers Street, Cambridge, MA 02142-1209, USA: MIT Press</publisher><subject>Adolescent ; Adult ; Brain ; Brain Hemisphere Functions ; Brain Mapping ; Choice Behavior - physiology ; Cognition & reasoning ; Cognitive Processes ; Decision Making ; Diagnostic Tests ; Female ; Functional Laterality ; Gambling - psychology ; Humans ; Image Processing, Computer-Assisted - methods ; Information processing ; Magnetic Resonance Imaging - methods ; Male ; Nerve Net - blood supply ; Nerve Net - physiology ; Neurosciences ; NMR ; Nuclear magnetic resonance ; Oxygen - blood ; Prefrontal Cortex - blood supply ; Prefrontal Cortex - physiology ; Stimuli ; Young Adult</subject><ispartof>Journal of cognitive neuroscience, 2009-10, Vol.21 (10), p.1956-1966</ispartof><rights>Copyright MIT Press Journals Oct 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c471t-54938f02f78ed374e1e54a2cde795075031ce1df931cf44aa9b090bf28d81cc03</citedby><cites>FETCH-LOGICAL-c471t-54938f02f78ed374e1e54a2cde795075031ce1df931cf44aa9b090bf28d81cc03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://direct.mit.edu/jocn/article/doi/10.1162/jocn.2008.21148$$EHTML$$P50$$Gmit$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,53984,53985</link.rule.ids><backlink>$$Uhttp://eric.ed.gov/ERICWebPortal/detail?accno=EJ864657$$DView record in ERIC$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18855544$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cunningham, William A.</creatorcontrib><creatorcontrib>Kesek, Amanda</creatorcontrib><creatorcontrib>Mowrer, Samantha M.</creatorcontrib><title>Distinct Orbitofrontal Regions Encode Stimulus and Choice Valuation</title><title>Journal of cognitive neuroscience</title><addtitle>J Cogn Neurosci</addtitle><description>The weak axiom of revealed preferences suggests that the value of an object can be understood through the simple examination of choices. Although this axiom has driven economic theory, the assumption of equation between value and choice is often violated. fMRI was used to decouple the processes associated with evaluating stimuli from evaluating one's actions. Whereas activity in left posterior areas of the orbitofrontal cortex (OFC) was associated with processing the objective value of stimuli, activity in medial anterior areas of the OFC was associated with accepting high value gambles and rejecting low value gambles; that is, making correct decisions. These data demonstrate that distinct areas of the OFC provide dissociated representations for use in adaptive decision-making and suggest an important processing distinction between the concepts of good/bad and right/wrong.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Brain</subject><subject>Brain Hemisphere Functions</subject><subject>Brain Mapping</subject><subject>Choice Behavior - physiology</subject><subject>Cognition & reasoning</subject><subject>Cognitive Processes</subject><subject>Decision Making</subject><subject>Diagnostic Tests</subject><subject>Female</subject><subject>Functional Laterality</subject><subject>Gambling - psychology</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted - methods</subject><subject>Information processing</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Nerve Net - blood supply</subject><subject>Nerve Net - physiology</subject><subject>Neurosciences</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Oxygen - blood</subject><subject>Prefrontal Cortex - blood supply</subject><subject>Prefrontal Cortex - physiology</subject><subject>Stimuli</subject><subject>Young Adult</subject><issn>0898-929X</issn><issn>1530-8898</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcFP2zAUxq0JNLqy8y4IRTvsMqU8O7ZjH6e2GyAkpAHTbpbrOOAqiYudTNr-epy1YhMCcfoO7-f3fX4fQh8wzDDm5GTtTTcjAGJGMKbiDZpgVkAuhBR7aAJJcknkzwP0LsY1ABDG6Vt0gIVgjFE6QfOFi73rTJ9dhpXrfR181-sm-25vne9ituyMr2x21bt2aIaY6a7K5nfeGZv90M2g-0Qdov1aN9G-3-kU3XxdXs9P84vLb2fzLxe5oSXuc0ZlIWogdSlsVZTUYsuoJqaypWRQMiiwsbiqZdKaUq3lCiSsaiIqgY2BYoo-bfdugr8fbOxV66KxTaM764eoeMkkx7x8FSQgeUnTpabo4xNw7YfQpU8oQgpgKRRP0MkWMsHHGGytNsG1OvxWGNTYghpbUGML6m8L6cXxbu2wam31j9-dPQFHW8AGZx7Hy3PBKWdj_sV23Lr_Eo0uvwh2ybUAQhgkS4JTApWM_7jNMzE-P7PmpdAPsdaucQ</recordid><startdate>20091001</startdate><enddate>20091001</enddate><creator>Cunningham, William A.</creator><creator>Kesek, Amanda</creator><creator>Mowrer, Samantha M.</creator><general>MIT Press</general><general>MIT Press Journals, The</general><scope>7SW</scope><scope>BJH</scope><scope>BNH</scope><scope>BNI</scope><scope>BNJ</scope><scope>BNO</scope><scope>ERI</scope><scope>PET</scope><scope>REK</scope><scope>WWN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QR</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20091001</creationdate><title>Distinct Orbitofrontal Regions Encode Stimulus and Choice Valuation</title><author>Cunningham, William A. ; Kesek, Amanda ; Mowrer, Samantha M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-54938f02f78ed374e1e54a2cde795075031ce1df931cf44aa9b090bf28d81cc03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Brain</topic><topic>Brain Hemisphere Functions</topic><topic>Brain Mapping</topic><topic>Choice Behavior - physiology</topic><topic>Cognition & reasoning</topic><topic>Cognitive Processes</topic><topic>Decision Making</topic><topic>Diagnostic Tests</topic><topic>Female</topic><topic>Functional Laterality</topic><topic>Gambling - psychology</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted - methods</topic><topic>Information processing</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Nerve Net - blood supply</topic><topic>Nerve Net - physiology</topic><topic>Neurosciences</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Oxygen - blood</topic><topic>Prefrontal Cortex - blood supply</topic><topic>Prefrontal Cortex - physiology</topic><topic>Stimuli</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cunningham, William A.</creatorcontrib><creatorcontrib>Kesek, Amanda</creatorcontrib><creatorcontrib>Mowrer, Samantha M.</creatorcontrib><collection>ERIC</collection><collection>ERIC (Ovid)</collection><collection>ERIC</collection><collection>ERIC</collection><collection>ERIC (Legacy Platform)</collection><collection>ERIC( SilverPlatter )</collection><collection>ERIC</collection><collection>ERIC PlusText (Legacy Platform)</collection><collection>Education Resources Information Center (ERIC)</collection><collection>ERIC</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cognitive neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cunningham, William A.</au><au>Kesek, Amanda</au><au>Mowrer, Samantha M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><ericid>EJ864657</ericid><atitle>Distinct Orbitofrontal Regions Encode Stimulus and Choice Valuation</atitle><jtitle>Journal of cognitive neuroscience</jtitle><addtitle>J Cogn Neurosci</addtitle><date>2009-10-01</date><risdate>2009</risdate><volume>21</volume><issue>10</issue><spage>1956</spage><epage>1966</epage><pages>1956-1966</pages><issn>0898-929X</issn><eissn>1530-8898</eissn><abstract>The weak axiom of revealed preferences suggests that the value of an object can be understood through the simple examination of choices. Although this axiom has driven economic theory, the assumption of equation between value and choice is often violated. fMRI was used to decouple the processes associated with evaluating stimuli from evaluating one's actions. Whereas activity in left posterior areas of the orbitofrontal cortex (OFC) was associated with processing the objective value of stimuli, activity in medial anterior areas of the OFC was associated with accepting high value gambles and rejecting low value gambles; that is, making correct decisions. These data demonstrate that distinct areas of the OFC provide dissociated representations for use in adaptive decision-making and suggest an important processing distinction between the concepts of good/bad and right/wrong.</abstract><cop>One Rogers Street, Cambridge, MA 02142-1209, USA</cop><pub>MIT Press</pub><pmid>18855544</pmid><doi>10.1162/jocn.2008.21148</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0898-929X |
| ispartof | Journal of cognitive neuroscience, 2009-10, Vol.21 (10), p.1956-1966 |
| issn | 0898-929X 1530-8898 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67596167 |
| source | MEDLINE; MIT Press Journals |
| subjects | Adolescent Adult Brain Brain Hemisphere Functions Brain Mapping Choice Behavior - physiology Cognition & reasoning Cognitive Processes Decision Making Diagnostic Tests Female Functional Laterality Gambling - psychology Humans Image Processing, Computer-Assisted - methods Information processing Magnetic Resonance Imaging - methods Male Nerve Net - blood supply Nerve Net - physiology Neurosciences NMR Nuclear magnetic resonance Oxygen - blood Prefrontal Cortex - blood supply Prefrontal Cortex - physiology Stimuli Young Adult |
| title | Distinct Orbitofrontal Regions Encode Stimulus and Choice Valuation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T19%3A39%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_mit_j&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Distinct%20Orbitofrontal%20Regions%20Encode%20Stimulus%20and%20Choice%20Valuation&rft.jtitle=Journal%20of%20cognitive%20neuroscience&rft.au=Cunningham,%20William%20A.&rft.date=2009-10-01&rft.volume=21&rft.issue=10&rft.spage=1956&rft.epage=1966&rft.pages=1956-1966&rft.issn=0898-929X&rft.eissn=1530-8898&rft_id=info:doi/10.1162/jocn.2008.21148&rft_dat=%3Cproquest_mit_j%3E20967415%3C/proquest_mit_j%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=223057506&rft_id=info:pmid/18855544&rft_ericid=EJ864657&rfr_iscdi=true |