A comparison of volatile and non volatile agents for cardioprotection during on‐pump coronary surgery
Summary A randomised study of 414 patients undergoing coronary artery surgery with cardiopulmonary bypass was conducted to compare the effects of a volatile anaesthetic regimen with either deesflurane or sevoflurane, and a total intravenous anaesthesia (TIVA) regimen on postoperative troponin T rele...
Gespeichert in:
| Veröffentlicht in: | Anaesthesia 2009-09, Vol.64 (9), p.953-960 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 960 |
|---|---|
| container_issue | 9 |
| container_start_page | 953 |
| container_title | Anaesthesia |
| container_volume | 64 |
| creator | De Hert, S. Vlasselaers, D. Barbé, R. Ory, J‐P. Dekegel, D. Donnadonni, R. Demeere, J‐L. Mulier, J. Wouters, P. |
| description | Summary
A randomised study of 414 patients undergoing coronary artery surgery with cardiopulmonary bypass was conducted to compare the effects of a volatile anaesthetic regimen with either deesflurane or sevoflurane, and a total intravenous anaesthesia (TIVA) regimen on postoperative troponin T release. The primary outcome variable was postoperative troponin T release, secondary outcome variables were hospital length of stay and 1‐year mortality. Maximal postoperative troponin T values did not differ between groups (TIVA: 0.30 [0.00–4.79] ng.ml−1 (median [range]), sevoflurane: 0.33 [0.02–3.68] ng.ml−1, and desflurane: 0.39 [0.08–3.74] ng.ml−1). The independent predictors of hospital length of stay were the EuroSCORE (p |
| doi_str_mv | 10.1111/j.1365-2044.2009.06008.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67594927</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67594927</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5418-f1f5fb044184cca4b985c6c438957a4084ef24fb389b643d5023b4da79c81e7e3</originalsourceid><addsrcrecordid>eNqNkc1u3CAUhVHVqJmkfYUKRWp3dvi1YRNpFKVNpSjZJGuEMYw8ssEFu8ns-gh9xj5JcWaUSF2FDXD57tHhHgAgRiXO63xbYlrxgiDGSoKQLFGFkCif3oHVy8N7sEII0YIwJI_BSUpbhDARWHwAx1hWomK1XIHNGpowjDp2KXgYHPwVej11vYXat9Dn2mthY_2UoAsRGh3bLowxTNZMXYbaOXZ-A4P_-_vPOA9jFo3B67iDaY4bG3cfwZHTfbKfDvspePh2dX95Xdzcff9xub4pDGdYFA477prsHgtmjGaNFNxUhlEhea0ZEsw6wlyT703FaMsRoQ1rdS2NwLa29BR83etmcz9nmyY1dMnYvtfehjmpquaSSVJn8Ow_cBvm6LM3hWVNec0pyZDYQyaGlKJ1aozdkL-lMFJLEmqrloGrZeBqSUI9J6Gecuvng_7cDLZ9bTyMPgNfDoBORvcuam-69MIRLAjGhGfuYs895hB2bzag1rfrq-VI_wHOT6Xn</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>197357532</pqid></control><display><type>article</type><title>A comparison of volatile and non volatile agents for cardioprotection during on‐pump coronary surgery</title><source>MEDLINE</source><source>Wiley Online Library Free Content</source><source>Access via Wiley Online Library</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>De Hert, S. ; Vlasselaers, D. ; Barbé, R. ; Ory, J‐P. ; Dekegel, D. ; Donnadonni, R. ; Demeere, J‐L. ; Mulier, J. ; Wouters, P.</creator><creatorcontrib>De Hert, S. ; Vlasselaers, D. ; Barbé, R. ; Ory, J‐P. ; Dekegel, D. ; Donnadonni, R. ; Demeere, J‐L. ; Mulier, J. ; Wouters, P.</creatorcontrib><description>Summary
A randomised study of 414 patients undergoing coronary artery surgery with cardiopulmonary bypass was conducted to compare the effects of a volatile anaesthetic regimen with either deesflurane or sevoflurane, and a total intravenous anaesthesia (TIVA) regimen on postoperative troponin T release. The primary outcome variable was postoperative troponin T release, secondary outcome variables were hospital length of stay and 1‐year mortality. Maximal postoperative troponin T values did not differ between groups (TIVA: 0.30 [0.00–4.79] ng.ml−1 (median [range]), sevoflurane: 0.33 [0.02–3.68] ng.ml−1, and desflurane: 0.39 [0.08–3.74] ng.ml−1). The independent predictors of hospital length of stay were the EuroSCORE (p < 0.001), female gender (p = 0.042) and the group assignment (p < 0.001). The one‐year mortality was 12.3% in the TIVA group, 3.3% in the sevoflurane group, and 6.7% in the desflurane group. The EuroSCORE (p = 0.003) was the only significant independent predictor of 1‐year mortality.</description><identifier>ISSN: 0003-2409</identifier><identifier>EISSN: 1365-2044</identifier><identifier>DOI: 10.1111/j.1365-2044.2009.06008.x</identifier><identifier>PMID: 19686479</identifier><identifier>CODEN: ANASAB</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Aged ; Anesthesia ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Anesthetics, Inhalation - therapeutic use ; Anesthetics, Intravenous - therapeutic use ; Biological and medical sciences ; Cardiopulmonary Bypass ; Cardiotonic Agents - therapeutic use ; Comparative studies ; Coronary Artery Bypass - methods ; Female ; Heart surgery ; Humans ; Ischemic Preconditioning, Myocardial - methods ; Isoflurane - analogs & derivatives ; Isoflurane - therapeutic use ; Length of Stay ; Male ; Medical sciences ; Methyl Ethers - therapeutic use ; Middle Aged ; Myocardial Reperfusion Injury - blood ; Myocardial Reperfusion Injury - prevention & control ; Postoperative Complications - prevention & control ; Risk Factors ; Survival Analysis ; Troponin T - blood</subject><ispartof>Anaesthesia, 2009-09, Vol.64 (9), p.953-960</ispartof><rights>2009 The Authors. Journal compilation © 2009 The Association of Anaesthetists of Great Britain and Ireland</rights><rights>2009 INIST-CNRS</rights><rights>2009 The Association of Anaesthetists of Great Britain and Ireland</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5418-f1f5fb044184cca4b985c6c438957a4084ef24fb389b643d5023b4da79c81e7e3</citedby><cites>FETCH-LOGICAL-c5418-f1f5fb044184cca4b985c6c438957a4084ef24fb389b643d5023b4da79c81e7e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2044.2009.06008.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2044.2009.06008.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,1433,27924,27925,45574,45575,46409,46833</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21821125$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19686479$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>De Hert, S.</creatorcontrib><creatorcontrib>Vlasselaers, D.</creatorcontrib><creatorcontrib>Barbé, R.</creatorcontrib><creatorcontrib>Ory, J‐P.</creatorcontrib><creatorcontrib>Dekegel, D.</creatorcontrib><creatorcontrib>Donnadonni, R.</creatorcontrib><creatorcontrib>Demeere, J‐L.</creatorcontrib><creatorcontrib>Mulier, J.</creatorcontrib><creatorcontrib>Wouters, P.</creatorcontrib><title>A comparison of volatile and non volatile agents for cardioprotection during on‐pump coronary surgery</title><title>Anaesthesia</title><addtitle>Anaesthesia</addtitle><description>Summary
A randomised study of 414 patients undergoing coronary artery surgery with cardiopulmonary bypass was conducted to compare the effects of a volatile anaesthetic regimen with either deesflurane or sevoflurane, and a total intravenous anaesthesia (TIVA) regimen on postoperative troponin T release. The primary outcome variable was postoperative troponin T release, secondary outcome variables were hospital length of stay and 1‐year mortality. Maximal postoperative troponin T values did not differ between groups (TIVA: 0.30 [0.00–4.79] ng.ml−1 (median [range]), sevoflurane: 0.33 [0.02–3.68] ng.ml−1, and desflurane: 0.39 [0.08–3.74] ng.ml−1). The independent predictors of hospital length of stay were the EuroSCORE (p < 0.001), female gender (p = 0.042) and the group assignment (p < 0.001). The one‐year mortality was 12.3% in the TIVA group, 3.3% in the sevoflurane group, and 6.7% in the desflurane group. The EuroSCORE (p = 0.003) was the only significant independent predictor of 1‐year mortality.</description><subject>Aged</subject><subject>Anesthesia</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Anesthetics, Inhalation - therapeutic use</subject><subject>Anesthetics, Intravenous - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Cardiopulmonary Bypass</subject><subject>Cardiotonic Agents - therapeutic use</subject><subject>Comparative studies</subject><subject>Coronary Artery Bypass - methods</subject><subject>Female</subject><subject>Heart surgery</subject><subject>Humans</subject><subject>Ischemic Preconditioning, Myocardial - methods</subject><subject>Isoflurane - analogs & derivatives</subject><subject>Isoflurane - therapeutic use</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Methyl Ethers - therapeutic use</subject><subject>Middle Aged</subject><subject>Myocardial Reperfusion Injury - blood</subject><subject>Myocardial Reperfusion Injury - prevention & control</subject><subject>Postoperative Complications - prevention & control</subject><subject>Risk Factors</subject><subject>Survival Analysis</subject><subject>Troponin T - blood</subject><issn>0003-2409</issn><issn>1365-2044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkc1u3CAUhVHVqJmkfYUKRWp3dvi1YRNpFKVNpSjZJGuEMYw8ssEFu8ns-gh9xj5JcWaUSF2FDXD57tHhHgAgRiXO63xbYlrxgiDGSoKQLFGFkCif3oHVy8N7sEII0YIwJI_BSUpbhDARWHwAx1hWomK1XIHNGpowjDp2KXgYHPwVej11vYXat9Dn2mthY_2UoAsRGh3bLowxTNZMXYbaOXZ-A4P_-_vPOA9jFo3B67iDaY4bG3cfwZHTfbKfDvspePh2dX95Xdzcff9xub4pDGdYFA477prsHgtmjGaNFNxUhlEhea0ZEsw6wlyT703FaMsRoQ1rdS2NwLa29BR83etmcz9nmyY1dMnYvtfehjmpquaSSVJn8Ow_cBvm6LM3hWVNec0pyZDYQyaGlKJ1aozdkL-lMFJLEmqrloGrZeBqSUI9J6Gecuvng_7cDLZ9bTyMPgNfDoBORvcuam-69MIRLAjGhGfuYs895hB2bzag1rfrq-VI_wHOT6Xn</recordid><startdate>200909</startdate><enddate>200909</enddate><creator>De Hert, S.</creator><creator>Vlasselaers, D.</creator><creator>Barbé, R.</creator><creator>Ory, J‐P.</creator><creator>Dekegel, D.</creator><creator>Donnadonni, R.</creator><creator>Demeere, J‐L.</creator><creator>Mulier, J.</creator><creator>Wouters, P.</creator><general>Blackwell Publishing Ltd</general><general>Wiley-Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U7</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>200909</creationdate><title>A comparison of volatile and non volatile agents for cardioprotection during on‐pump coronary surgery</title><author>De Hert, S. ; Vlasselaers, D. ; Barbé, R. ; Ory, J‐P. ; Dekegel, D. ; Donnadonni, R. ; Demeere, J‐L. ; Mulier, J. ; Wouters, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5418-f1f5fb044184cca4b985c6c438957a4084ef24fb389b643d5023b4da79c81e7e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Aged</topic><topic>Anesthesia</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Anesthetics, Inhalation - therapeutic use</topic><topic>Anesthetics, Intravenous - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Cardiopulmonary Bypass</topic><topic>Cardiotonic Agents - therapeutic use</topic><topic>Comparative studies</topic><topic>Coronary Artery Bypass - methods</topic><topic>Female</topic><topic>Heart surgery</topic><topic>Humans</topic><topic>Ischemic Preconditioning, Myocardial - methods</topic><topic>Isoflurane - analogs & derivatives</topic><topic>Isoflurane - therapeutic use</topic><topic>Length of Stay</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Methyl Ethers - therapeutic use</topic><topic>Middle Aged</topic><topic>Myocardial Reperfusion Injury - blood</topic><topic>Myocardial Reperfusion Injury - prevention & control</topic><topic>Postoperative Complications - prevention & control</topic><topic>Risk Factors</topic><topic>Survival Analysis</topic><topic>Troponin T - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>De Hert, S.</creatorcontrib><creatorcontrib>Vlasselaers, D.</creatorcontrib><creatorcontrib>Barbé, R.</creatorcontrib><creatorcontrib>Ory, J‐P.</creatorcontrib><creatorcontrib>Dekegel, D.</creatorcontrib><creatorcontrib>Donnadonni, R.</creatorcontrib><creatorcontrib>Demeere, J‐L.</creatorcontrib><creatorcontrib>Mulier, J.</creatorcontrib><creatorcontrib>Wouters, P.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Anaesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>De Hert, S.</au><au>Vlasselaers, D.</au><au>Barbé, R.</au><au>Ory, J‐P.</au><au>Dekegel, D.</au><au>Donnadonni, R.</au><au>Demeere, J‐L.</au><au>Mulier, J.</au><au>Wouters, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comparison of volatile and non volatile agents for cardioprotection during on‐pump coronary surgery</atitle><jtitle>Anaesthesia</jtitle><addtitle>Anaesthesia</addtitle><date>2009-09</date><risdate>2009</risdate><volume>64</volume><issue>9</issue><spage>953</spage><epage>960</epage><pages>953-960</pages><issn>0003-2409</issn><eissn>1365-2044</eissn><coden>ANASAB</coden><abstract>Summary
A randomised study of 414 patients undergoing coronary artery surgery with cardiopulmonary bypass was conducted to compare the effects of a volatile anaesthetic regimen with either deesflurane or sevoflurane, and a total intravenous anaesthesia (TIVA) regimen on postoperative troponin T release. The primary outcome variable was postoperative troponin T release, secondary outcome variables were hospital length of stay and 1‐year mortality. Maximal postoperative troponin T values did not differ between groups (TIVA: 0.30 [0.00–4.79] ng.ml−1 (median [range]), sevoflurane: 0.33 [0.02–3.68] ng.ml−1, and desflurane: 0.39 [0.08–3.74] ng.ml−1). The independent predictors of hospital length of stay were the EuroSCORE (p < 0.001), female gender (p = 0.042) and the group assignment (p < 0.001). The one‐year mortality was 12.3% in the TIVA group, 3.3% in the sevoflurane group, and 6.7% in the desflurane group. The EuroSCORE (p = 0.003) was the only significant independent predictor of 1‐year mortality.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>19686479</pmid><doi>10.1111/j.1365-2044.2009.06008.x</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-2409 |
| ispartof | Anaesthesia, 2009-09, Vol.64 (9), p.953-960 |
| issn | 0003-2409 1365-2044 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67594927 |
| source | MEDLINE; Wiley Online Library Free Content; Access via Wiley Online Library; EZB-FREE-00999 freely available EZB journals |
| subjects | Aged Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthetics, Inhalation - therapeutic use Anesthetics, Intravenous - therapeutic use Biological and medical sciences Cardiopulmonary Bypass Cardiotonic Agents - therapeutic use Comparative studies Coronary Artery Bypass - methods Female Heart surgery Humans Ischemic Preconditioning, Myocardial - methods Isoflurane - analogs & derivatives Isoflurane - therapeutic use Length of Stay Male Medical sciences Methyl Ethers - therapeutic use Middle Aged Myocardial Reperfusion Injury - blood Myocardial Reperfusion Injury - prevention & control Postoperative Complications - prevention & control Risk Factors Survival Analysis Troponin T - blood |
| title | A comparison of volatile and non volatile agents for cardioprotection during on‐pump coronary surgery |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T17%3A01%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20comparison%20of%20volatile%20and%20non%20volatile%20agents%20for%20cardioprotection%20during%20on%E2%80%90pump%20coronary%20surgery&rft.jtitle=Anaesthesia&rft.au=De%20Hert,%20S.&rft.date=2009-09&rft.volume=64&rft.issue=9&rft.spage=953&rft.epage=960&rft.pages=953-960&rft.issn=0003-2409&rft.eissn=1365-2044&rft.coden=ANASAB&rft_id=info:doi/10.1111/j.1365-2044.2009.06008.x&rft_dat=%3Cproquest_cross%3E67594927%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=197357532&rft_id=info:pmid/19686479&rfr_iscdi=true |