An unexpected effect of 5‐MCA‐NAT in chick retinal development

Luzindole is an unselective antagonist of the melatonin receptors and melatonin's other binding sites, although some exceptions have been observed in chick retinal neurodevelopment, where this unselective antagonist does not block melatonin's inhibitory effect on the adenylate cyclase enzy...

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Veröffentlicht in:	International journal of developmental neuroscience 2009-10, Vol.27 (6), p.511-515
1. Verfasser:	Fatima Sobral Sampaio, Lucia
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Animals Binding Sites - drug effects Binding Sites - physiology Chick Embryo Chickens Colforsin - pharmacology Cyclic AMP - metabolism Dose-Response Relationship, Drug Luzindole Melatonin Melatonin - antagonists & inhibitors Melatonin - metabolism MT3 Neurodevelopment Neurogenesis - drug effects Neurogenesis - physiology Neurons - drug effects Neurons - metabolism Organ Culture Techniques Organogenesis - drug effects Organogenesis - physiology QR2 physiology Quinone Reductases - drug effects Quinone Reductases - metabolism Receptors, G-Protein-Coupled - drug effects Receptors, G-Protein-Coupled - metabolism Receptors, Melatonin - agonists Receptors, Melatonin - antagonists & inhibitors Receptors, Melatonin - metabolism Retina Retina - drug effects Retina - embryology Retina - growth & development Second Messenger Systems - drug effects Second Messenger Systems - physiology Tryptamines - pharmacology Up-Regulation - drug effects Up-Regulation - physiology
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