CT-guided Blocks and Neuroablation of the Ganglion Impar (Walther) in Perineal Pain: Anatomy, Technique, Safety, and Efficacy

OBJECTIVEAn alternate approach to the ganglion impar was chosen to minimize the risk of adverse events. Efficacy of the procedure was evaluated. METHODSCharts and computed tomography (CT)-scans of patients who underwent block and neuroablation of the ganglion impar (Walther) between 2003 and 2007 we...

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Veröffentlicht in:The Clinical journal of pain 2009-09, Vol.25 (7), p.570-576
Hauptverfasser: Agarwal-Kozlowski, Kamayni, Lorke, Dietrich E, Habermann, Christian R, am Esch, Jochen Schulte, Beck, Helge
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container_end_page 576
container_issue 7
container_start_page 570
container_title The Clinical journal of pain
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creator Agarwal-Kozlowski, Kamayni
Lorke, Dietrich E
Habermann, Christian R
am Esch, Jochen Schulte
Beck, Helge
description OBJECTIVEAn alternate approach to the ganglion impar was chosen to minimize the risk of adverse events. Efficacy of the procedure was evaluated. METHODSCharts and computed tomography (CT)-scans of patients who underwent block and neuroablation of the ganglion impar (Walther) between 2003 and 2007 were systematically reviewed with respect to adverse events and efficacy by rating pain intensity. A total of 76 blocks were performed, 48 of them being diagnostic blocks and 28 neuroablations. Chemical destruction was performed with ethanol, if pain recurred despite injection of local anesthetic. RESULTSInterventional pain therapy was performed in 43 patients (age64.6±12.4 y, median 49.5 y, range36 to 86 y, male/female27/16) presenting with perineal pain of unknown origin (n=15), carcinoma of the prostate (n=8), colorectal carcinoma (n=7), postsurgery of thrombosis of perineal veins (n=3), postherpetic neuralgia (n=4), malformation of the spinal cord (n=2), vaginal protrusion (n=2), failed back surgery syndrome (n=1), and ablation of testis (n=1). CT-guided puncture was not associated with any adverse events and resulted in a reduction of numeric rating scale values from 8.2±1.6 to 2.2±1.6 (P
doi_str_mv 10.1097/AJP.0b013e3181a5f5c7
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Efficacy of the procedure was evaluated. METHODSCharts and computed tomography (CT)-scans of patients who underwent block and neuroablation of the ganglion impar (Walther) between 2003 and 2007 were systematically reviewed with respect to adverse events and efficacy by rating pain intensity. A total of 76 blocks were performed, 48 of them being diagnostic blocks and 28 neuroablations. Chemical destruction was performed with ethanol, if pain recurred despite injection of local anesthetic. RESULTSInterventional pain therapy was performed in 43 patients (age64.6±12.4 y, median 49.5 y, range36 to 86 y, male/female27/16) presenting with perineal pain of unknown origin (n=15), carcinoma of the prostate (n=8), colorectal carcinoma (n=7), postsurgery of thrombosis of perineal veins (n=3), postherpetic neuralgia (n=4), malformation of the spinal cord (n=2), vaginal protrusion (n=2), failed back surgery syndrome (n=1), and ablation of testis (n=1). CT-guided puncture was not associated with any adverse events and resulted in a reduction of numeric rating scale values from 8.2±1.6 to 2.2±1.6 (P&lt;0.0001, 95% confidence interval 0.5) immediately at discharge and to 2.2±1.4 (P&lt;0.0001, 95% confidence interval 0.4) at 4 months on follow up. DISCUSSIONCT-guided block and neuroablation of the ganglion impar (Walther) results in a significant reduction of pain scores and carries virtually no hazards.</description><identifier>ISSN: 0749-8047</identifier><identifier>EISSN: 1536-5409</identifier><identifier>DOI: 10.1097/AJP.0b013e3181a5f5c7</identifier><identifier>PMID: 19692797</identifier><identifier>CODEN: CJPAEU</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams &amp; Wilkins, Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Anatomy ; Biological and medical sciences ; Central nervous system ; Female ; Fundamental and applied biological sciences. Psychology ; Ganglia, Sympathetic - injuries ; Ganglia, Sympathetic - surgery ; Humans ; Male ; Medical sciences ; Middle Aged ; Nerve Block - methods ; Neuralgia - diagnostic imaging ; Neuralgia - etiology ; Neuralgia - pathology ; Neuralgia - surgery ; Neurology ; Pain Measurement - methods ; Pelvic Pain - diagnostic imaging ; Pelvic Pain - pathology ; Pelvic Pain - surgery ; Retrospective Studies ; Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. 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Efficacy of the procedure was evaluated. METHODSCharts and computed tomography (CT)-scans of patients who underwent block and neuroablation of the ganglion impar (Walther) between 2003 and 2007 were systematically reviewed with respect to adverse events and efficacy by rating pain intensity. A total of 76 blocks were performed, 48 of them being diagnostic blocks and 28 neuroablations. Chemical destruction was performed with ethanol, if pain recurred despite injection of local anesthetic. RESULTSInterventional pain therapy was performed in 43 patients (age64.6±12.4 y, median 49.5 y, range36 to 86 y, male/female27/16) presenting with perineal pain of unknown origin (n=15), carcinoma of the prostate (n=8), colorectal carcinoma (n=7), postsurgery of thrombosis of perineal veins (n=3), postherpetic neuralgia (n=4), malformation of the spinal cord (n=2), vaginal protrusion (n=2), failed back surgery syndrome (n=1), and ablation of testis (n=1). CT-guided puncture was not associated with any adverse events and resulted in a reduction of numeric rating scale values from 8.2±1.6 to 2.2±1.6 (P&lt;0.0001, 95% confidence interval 0.5) immediately at discharge and to 2.2±1.4 (P&lt;0.0001, 95% confidence interval 0.4) at 4 months on follow up. DISCUSSIONCT-guided block and neuroablation of the ganglion impar (Walther) results in a significant reduction of pain scores and carries virtually no hazards.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anatomy</subject><subject>Biological and medical sciences</subject><subject>Central nervous system</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Ganglia, Sympathetic - injuries</subject><subject>Ganglia, Sympathetic - surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nerve Block - methods</subject><subject>Neuralgia - diagnostic imaging</subject><subject>Neuralgia - etiology</subject><subject>Neuralgia - pathology</subject><subject>Neuralgia - surgery</subject><subject>Neurology</subject><subject>Pain Measurement - methods</subject><subject>Pelvic Pain - diagnostic imaging</subject><subject>Pelvic Pain - pathology</subject><subject>Pelvic Pain - surgery</subject><subject>Retrospective Studies</subject><subject>Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0749-8047</issn><issn>1536-5409</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkEFv1DAQhSMEokvhHyDkCwikpoztJLa5LatSiipYiUUco4kz6Zo6yWInqvbAf8errgAxPoz89M2b0cuy5xzOORj1dvlpfQ4NcEmSa45lV1r1IFvwUlZ5WYB5mC1AFSbXUKiT7EmMPwB4KTQ8zk64qYxQRi2yX6tNfjO7llr23o_2NjIcWvaZ5jBi43Fy48DGjk1bYpc43PjD_6rfYWCvv6NPcnjD3MDWFNxA6Nka3fCOLQecxn5_xjZkt4P7OdMZ-4odTUk6-F90nbNo90-zRx36SM-O_TT79uFis_qYX3-5vFotr3MrhZG5aiUXLVatJpIFKNMp6CqlhECjdFPoVmJbFppAaUVlZQ1yEJigRnDdkDzNXt377sKYjolT3btoyXscaJxjXanS8KrQCSzuQRvGGAN19S64HsO-5lAfYq9T7PX_saexF0f_uemp_Tt0zDkBL48ARou-CzhYF_9w6UpVGfPP_rvRTxTirZ_vKNRbOmRdQypRgs4FgEkPID9IUv4GWFGa0Q</recordid><startdate>200909</startdate><enddate>200909</enddate><creator>Agarwal-Kozlowski, Kamayni</creator><creator>Lorke, Dietrich E</creator><creator>Habermann, Christian R</creator><creator>am Esch, Jochen Schulte</creator><creator>Beck, Helge</creator><general>Lippincott Williams &amp; Wilkins, Inc</general><general>Lippincott Williams &amp; Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200909</creationdate><title>CT-guided Blocks and Neuroablation of the Ganglion Impar (Walther) in Perineal Pain: Anatomy, Technique, Safety, and Efficacy</title><author>Agarwal-Kozlowski, Kamayni ; Lorke, Dietrich E ; Habermann, Christian R ; am Esch, Jochen Schulte ; Beck, Helge</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3293-7d312da6d8ee34079f70f67722a978b48d3ad548e0787e56c9a102a70fb218be3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anatomy</topic><topic>Biological and medical sciences</topic><topic>Central nervous system</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Ganglia, Sympathetic - injuries</topic><topic>Ganglia, Sympathetic - surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nerve Block - methods</topic><topic>Neuralgia - diagnostic imaging</topic><topic>Neuralgia - etiology</topic><topic>Neuralgia - pathology</topic><topic>Neuralgia - surgery</topic><topic>Neurology</topic><topic>Pain Measurement - methods</topic><topic>Pelvic Pain - diagnostic imaging</topic><topic>Pelvic Pain - pathology</topic><topic>Pelvic Pain - surgery</topic><topic>Retrospective Studies</topic><topic>Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Agarwal-Kozlowski, Kamayni</creatorcontrib><creatorcontrib>Lorke, Dietrich E</creatorcontrib><creatorcontrib>Habermann, Christian R</creatorcontrib><creatorcontrib>am Esch, Jochen Schulte</creatorcontrib><creatorcontrib>Beck, Helge</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Clinical journal of pain</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Agarwal-Kozlowski, Kamayni</au><au>Lorke, Dietrich E</au><au>Habermann, Christian R</au><au>am Esch, Jochen Schulte</au><au>Beck, Helge</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>CT-guided Blocks and Neuroablation of the Ganglion Impar (Walther) in Perineal Pain: Anatomy, Technique, Safety, and Efficacy</atitle><jtitle>The Clinical journal of pain</jtitle><addtitle>Clin J Pain</addtitle><date>2009-09</date><risdate>2009</risdate><volume>25</volume><issue>7</issue><spage>570</spage><epage>576</epage><pages>570-576</pages><issn>0749-8047</issn><eissn>1536-5409</eissn><coden>CJPAEU</coden><abstract>OBJECTIVEAn alternate approach to the ganglion impar was chosen to minimize the risk of adverse events. Efficacy of the procedure was evaluated. METHODSCharts and computed tomography (CT)-scans of patients who underwent block and neuroablation of the ganglion impar (Walther) between 2003 and 2007 were systematically reviewed with respect to adverse events and efficacy by rating pain intensity. A total of 76 blocks were performed, 48 of them being diagnostic blocks and 28 neuroablations. Chemical destruction was performed with ethanol, if pain recurred despite injection of local anesthetic. RESULTSInterventional pain therapy was performed in 43 patients (age64.6±12.4 y, median 49.5 y, range36 to 86 y, male/female27/16) presenting with perineal pain of unknown origin (n=15), carcinoma of the prostate (n=8), colorectal carcinoma (n=7), postsurgery of thrombosis of perineal veins (n=3), postherpetic neuralgia (n=4), malformation of the spinal cord (n=2), vaginal protrusion (n=2), failed back surgery syndrome (n=1), and ablation of testis (n=1). CT-guided puncture was not associated with any adverse events and resulted in a reduction of numeric rating scale values from 8.2±1.6 to 2.2±1.6 (P&lt;0.0001, 95% confidence interval 0.5) immediately at discharge and to 2.2±1.4 (P&lt;0.0001, 95% confidence interval 0.4) at 4 months on follow up. DISCUSSIONCT-guided block and neuroablation of the ganglion impar (Walther) results in a significant reduction of pain scores and carries virtually no hazards.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams &amp; Wilkins, Inc</pub><pmid>19692797</pmid><doi>10.1097/AJP.0b013e3181a5f5c7</doi><tpages>7</tpages></addata></record>
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subjects Adult
Aged
Aged, 80 and over
Anatomy
Biological and medical sciences
Central nervous system
Female
Fundamental and applied biological sciences. Psychology
Ganglia, Sympathetic - injuries
Ganglia, Sympathetic - surgery
Humans
Male
Medical sciences
Middle Aged
Nerve Block - methods
Neuralgia - diagnostic imaging
Neuralgia - etiology
Neuralgia - pathology
Neuralgia - surgery
Neurology
Pain Measurement - methods
Pelvic Pain - diagnostic imaging
Pelvic Pain - pathology
Pelvic Pain - surgery
Retrospective Studies
Somesthesis and somesthetic pathways (proprioception, exteroception, nociception)
interoception
electrolocation. Sensory receptors
Tomography, X-Ray Computed - methods
Vertebrates: nervous system and sense organs
title CT-guided Blocks and Neuroablation of the Ganglion Impar (Walther) in Perineal Pain: Anatomy, Technique, Safety, and Efficacy
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