EUROPLUS™ ANCA BIOCHIP mosaic: PR3 and MPO antigen microdots improve the laboratory diagnostics of ANCA-associated vasculitis

The consensus on anti-neutrophil cytoplasmic antibody (ANCA) testing requires screening with indirect immunofluorescence (IIF) and confirmation in MPO- and PR3-ANCA specific assays. The EUROPLUS™ system combines in one incubation the conventional cell substrates with microdots of single antigens, i....

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Veröffentlicht in:	Journal of immunological methods 2009-08, Vol.348 (1), p.67-73
Hauptverfasser:	Damoiseaux, Jan, Steller, Ulf, Buschtez, Michael, Vaessen, Mia, Rosemann, Anke, van Paassen, Pieter, Stöcker, Winfried, Fechner, Kai, Cohen Tervaert, Jan Willem
Format:	Artikel
Sprache:	eng
Schlagworte:	Adeno-associated virus Algorithms Anti-neutrophil cytoplasmic antibodies Antibodies, Antineutrophil Cytoplasmic - blood Autoantibodies Autoantibodies - blood Autoimmune Diseases - diagnosis Autoimmune Diseases - immunology Biological and medical sciences Cohort Studies Cross-Sectional Studies Fundamental and applied biological sciences. Psychology Fundamental immunology Granulocyte Colony-Stimulating Factor - analysis Granulomatosis with Polyangiitis - blood Granulomatosis with Polyangiitis - diagnosis Humans Immunoassay Interleukin-3 - analysis Molecular immunology Myeloblastin - analysis Protein Array Analysis Reagent Kits, Diagnostic Recombinant Fusion Proteins - analysis Recombinant Proteins Sensitivity and Specificity Techniques Vasculitis
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