Low incidence of mutations in EGFR kinase domain in Caucasian patients with head and neck squamous cell carcinoma

Somatic mutations in the tyrosine kinase domain of the epidermal growth factor receptor ( EGFR) gene are associated with increased sensitivity to tyrosine kinase inhibitors (TKIs) and are present in 10–30% of non-small cell lung carcinoma depending on ethnic origin. EGFR protein is also overexpresse...

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