Can d -dimer become a new diagnostic parameter for acute appendicitis?
Abstract Introduction In this study, we investigated d -dimer serum level as a diagnostic parameter for acute appendicitis. Materials and Methods Forty-nine patients were enrolled in the study. Patients were classified according to age; sex; duration between the beginning of pain and referral to a h...
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| Veröffentlicht in: | The American journal of emergency medicine 2009-09, Vol.27 (7), p.765-769 |
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| container_title | The American journal of emergency medicine |
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| creator | Mentes, Oner, MD Eryilmaz, Mehmet, MD Harlak, Ali, MD Ozer, Tahir, MD Balkan, Mujdat, MD Kozak, Orhan, MD Tufan, Turgut, MD |
| description | Abstract Introduction In this study, we investigated d -dimer serum level as a diagnostic parameter for acute appendicitis. Materials and Methods Forty-nine patients were enrolled in the study. Patients were classified according to age; sex; duration between the beginning of pain and referral to a hospital or clinic; Alvarado scores; and in physical examination, presence of muscular defense, the number of leukocytes, preoperative ultrasonography, and d -dimer levels of histopathologic study groups were analyzed. Results Of the patients enrolled in the study, 26.5% were females and 73.5% males. The average age was 21 years (range, 16-38 years) and 81.7% acute appendicitis (AA). According the duration of pain, 63.2% of the patients were referred to the hospital within the first 24 hours, 26.5% of the patients were referred to the hospital within 24 to 48 hours, and 10.3% were referred to the hospital within a period of more than 48 hours. No statistically significant difference was determined regarding d -dimer levels between the histopathologic study groups ( P > .05). Alvarado scores lower than 7 were found in 36.7% and 7 or higher in 63.3% of the patients. There was no statistically significant difference related with d -dimer levels between histopathologic study groups ( P > .05). The ratio of cases with a number of leukocytes below the upper limit were determined respectively as 32.7% and 67.3%, and no statistically significant difference was found regarding d -dimer levels between histopathologic study groups ( P > .05). Conclusion Increased d -dimer levels should not be considered as a diagnostic parameter in diagnosis of acute appendicitis. |
| doi_str_mv | 10.1016/j.ajem.2008.06.001 |
| format | Article |
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Materials and Methods Forty-nine patients were enrolled in the study. Patients were classified according to age; sex; duration between the beginning of pain and referral to a hospital or clinic; Alvarado scores; and in physical examination, presence of muscular defense, the number of leukocytes, preoperative ultrasonography, and d -dimer levels of histopathologic study groups were analyzed. Results Of the patients enrolled in the study, 26.5% were females and 73.5% males. The average age was 21 years (range, 16-38 years) and 81.7% acute appendicitis (AA). According the duration of pain, 63.2% of the patients were referred to the hospital within the first 24 hours, 26.5% of the patients were referred to the hospital within 24 to 48 hours, and 10.3% were referred to the hospital within a period of more than 48 hours. No statistically significant difference was determined regarding d -dimer levels between the histopathologic study groups ( P > .05). Alvarado scores lower than 7 were found in 36.7% and 7 or higher in 63.3% of the patients. There was no statistically significant difference related with d -dimer levels between histopathologic study groups ( P > .05). The ratio of cases with a number of leukocytes below the upper limit were determined respectively as 32.7% and 67.3%, and no statistically significant difference was found regarding d -dimer levels between histopathologic study groups ( P > .05). Conclusion Increased d -dimer levels should not be considered as a diagnostic parameter in diagnosis of acute appendicitis.</description><identifier>ISSN: 0735-6757</identifier><identifier>EISSN: 1532-8171</identifier><identifier>DOI: 10.1016/j.ajem.2008.06.001</identifier><identifier>PMID: 19683101</identifier><identifier>CODEN: AJEMEN</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Abdomen ; Acute Disease ; Adolescent ; Adult ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Appendicitis ; Appendicitis - diagnosis ; Biological and medical sciences ; Emergency ; Emergency medical care ; Female ; Fibrin Fibrinogen Degradation Products - analysis ; Humans ; Intensive care medicine ; Ischemia ; Male ; Medical diagnosis ; Medical sciences ; Mortality ; Pain ; Pneumology ; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases ; Retrospective Studies ; Sensitivity and Specificity ; Veins & arteries ; Young Adult</subject><ispartof>The American journal of emergency medicine, 2009-09, Vol.27 (7), p.765-769</ispartof><rights>Elsevier Inc.</rights><rights>2009 Elsevier Inc.</rights><rights>2009 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c467t-8adc9d7569ffd08a82b229647e3f9e6e03dbf112546079a22bc39acd926da37c3</citedby><cites>FETCH-LOGICAL-c467t-8adc9d7569ffd08a82b229647e3f9e6e03dbf112546079a22bc39acd926da37c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0735675708004191$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21860200$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19683101$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mentes, Oner, MD</creatorcontrib><creatorcontrib>Eryilmaz, Mehmet, MD</creatorcontrib><creatorcontrib>Harlak, Ali, MD</creatorcontrib><creatorcontrib>Ozer, Tahir, MD</creatorcontrib><creatorcontrib>Balkan, Mujdat, MD</creatorcontrib><creatorcontrib>Kozak, Orhan, MD</creatorcontrib><creatorcontrib>Tufan, Turgut, MD</creatorcontrib><title>Can d -dimer become a new diagnostic parameter for acute appendicitis?</title><title>The American journal of emergency medicine</title><addtitle>Am J Emerg Med</addtitle><description>Abstract Introduction In this study, we investigated d -dimer serum level as a diagnostic parameter for acute appendicitis. Materials and Methods Forty-nine patients were enrolled in the study. Patients were classified according to age; sex; duration between the beginning of pain and referral to a hospital or clinic; Alvarado scores; and in physical examination, presence of muscular defense, the number of leukocytes, preoperative ultrasonography, and d -dimer levels of histopathologic study groups were analyzed. Results Of the patients enrolled in the study, 26.5% were females and 73.5% males. The average age was 21 years (range, 16-38 years) and 81.7% acute appendicitis (AA). According the duration of pain, 63.2% of the patients were referred to the hospital within the first 24 hours, 26.5% of the patients were referred to the hospital within 24 to 48 hours, and 10.3% were referred to the hospital within a period of more than 48 hours. No statistically significant difference was determined regarding d -dimer levels between the histopathologic study groups ( P > .05). Alvarado scores lower than 7 were found in 36.7% and 7 or higher in 63.3% of the patients. There was no statistically significant difference related with d -dimer levels between histopathologic study groups ( P > .05). The ratio of cases with a number of leukocytes below the upper limit were determined respectively as 32.7% and 67.3%, and no statistically significant difference was found regarding d -dimer levels between histopathologic study groups ( P > .05). Conclusion Increased d -dimer levels should not be considered as a diagnostic parameter in diagnosis of acute appendicitis.</description><subject>Abdomen</subject><subject>Acute Disease</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Appendicitis</subject><subject>Appendicitis - diagnosis</subject><subject>Biological and medical sciences</subject><subject>Emergency</subject><subject>Emergency medical care</subject><subject>Female</subject><subject>Fibrin Fibrinogen Degradation Products - analysis</subject><subject>Humans</subject><subject>Intensive care medicine</subject><subject>Ischemia</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>Medical sciences</subject><subject>Mortality</subject><subject>Pain</subject><subject>Pneumology</subject><subject>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. 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Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Appendicitis</topic><topic>Appendicitis - diagnosis</topic><topic>Biological and medical sciences</topic><topic>Emergency</topic><topic>Emergency medical care</topic><topic>Female</topic><topic>Fibrin Fibrinogen Degradation Products - analysis</topic><topic>Humans</topic><topic>Intensive care medicine</topic><topic>Ischemia</topic><topic>Male</topic><topic>Medical diagnosis</topic><topic>Medical sciences</topic><topic>Mortality</topic><topic>Pain</topic><topic>Pneumology</topic><topic>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. 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Materials and Methods Forty-nine patients were enrolled in the study. Patients were classified according to age; sex; duration between the beginning of pain and referral to a hospital or clinic; Alvarado scores; and in physical examination, presence of muscular defense, the number of leukocytes, preoperative ultrasonography, and d -dimer levels of histopathologic study groups were analyzed. Results Of the patients enrolled in the study, 26.5% were females and 73.5% males. The average age was 21 years (range, 16-38 years) and 81.7% acute appendicitis (AA). According the duration of pain, 63.2% of the patients were referred to the hospital within the first 24 hours, 26.5% of the patients were referred to the hospital within 24 to 48 hours, and 10.3% were referred to the hospital within a period of more than 48 hours. No statistically significant difference was determined regarding d -dimer levels between the histopathologic study groups ( P > .05). Alvarado scores lower than 7 were found in 36.7% and 7 or higher in 63.3% of the patients. There was no statistically significant difference related with d -dimer levels between histopathologic study groups ( P > .05). The ratio of cases with a number of leukocytes below the upper limit were determined respectively as 32.7% and 67.3%, and no statistically significant difference was found regarding d -dimer levels between histopathologic study groups ( P > .05). Conclusion Increased d -dimer levels should not be considered as a diagnostic parameter in diagnosis of acute appendicitis.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>19683101</pmid><doi>10.1016/j.ajem.2008.06.001</doi><tpages>5</tpages></addata></record> |
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| subjects | Abdomen Acute Disease Adolescent Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Appendicitis Appendicitis - diagnosis Biological and medical sciences Emergency Emergency medical care Female Fibrin Fibrinogen Degradation Products - analysis Humans Intensive care medicine Ischemia Male Medical diagnosis Medical sciences Mortality Pain Pneumology Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases Retrospective Studies Sensitivity and Specificity Veins & arteries Young Adult |
| title | Can d -dimer become a new diagnostic parameter for acute appendicitis? |
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