Floating intra-aortic thrombus presenting as distal arterial embolism
Department of Cardiothoracic Surgery, Wessex Cardiac Unit, Southampton General Hospital, Southampton, UK *Corresponding author. 105 Captains Place, Southampton SO14 3TF, Hampshire, UK. Tel.: +447970539749. E-mail address : dpousios{at}yahoo.com (D. Pousios). Floating thrombi in the aorta are a rare...
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creator | Pousios, Dimitrios Velissaris, Theodoros Duggan, Simon Tsang, Geoff |
description | Department of Cardiothoracic Surgery, Wessex Cardiac Unit, Southampton General Hospital, Southampton, UK
*Corresponding author. 105 Captains Place, Southampton SO14 3TF, Hampshire, UK. Tel.: +447970539749. E-mail address : dpousios{at}yahoo.com (D. Pousios).
Floating thrombi in the aorta are a rare finding in the absence of any coagulation abnormality. They often represent a surgical emergency. Our case refers to a 45-year-old woman who presented with acute ischemia of the upper extremity. This was a result of peripheral embolism originating in a floating thrombus in the ascending aorta. A free-floating lesion held by a pedicle from the lateral ascending aortic wall was demonstrated using computed tomography and magnetic resonance scans. There was no pre-existing clotting abnormality. Conservative treatment with oral anticoagulation was not successful in removing the lesion. Therefore, a surgical approach was selected through a median sternotomy and cardiopulmonary bypass. Under temporary hypothermic circulatory arrest, the ascending aorta was opened. The lesion was removed along with a rim of aortic wall, circulation was re-established and the aorta was reconnected with use of a synthetic interposition graft. Postoperative course was uneventful. The patient was discharged on oral anticoagulation. Histopathology confirmed the lesion as thrombus. Only a few cases of intra-aortic thrombus without any coagulation abnormality basis are described in literature. Occasionally, they present as distal embolism. Treatment should be surgical excision on cardiopulmonary bypass, a procedure performed safely with excellent outcome.
Key Words: Ascending aorta; Embolism; Thrombosis; Cardiopulmonary bypass |
doi_str_mv | 10.1510/icvts.2009.206268 |
format | Article |
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*Corresponding author. 105 Captains Place, Southampton SO14 3TF, Hampshire, UK. Tel.: +447970539749. E-mail address : dpousios{at}yahoo.com (D. Pousios).
Floating thrombi in the aorta are a rare finding in the absence of any coagulation abnormality. They often represent a surgical emergency. Our case refers to a 45-year-old woman who presented with acute ischemia of the upper extremity. This was a result of peripheral embolism originating in a floating thrombus in the ascending aorta. A free-floating lesion held by a pedicle from the lateral ascending aortic wall was demonstrated using computed tomography and magnetic resonance scans. There was no pre-existing clotting abnormality. Conservative treatment with oral anticoagulation was not successful in removing the lesion. Therefore, a surgical approach was selected through a median sternotomy and cardiopulmonary bypass. Under temporary hypothermic circulatory arrest, the ascending aorta was opened. The lesion was removed along with a rim of aortic wall, circulation was re-established and the aorta was reconnected with use of a synthetic interposition graft. Postoperative course was uneventful. The patient was discharged on oral anticoagulation. Histopathology confirmed the lesion as thrombus. Only a few cases of intra-aortic thrombus without any coagulation abnormality basis are described in literature. Occasionally, they present as distal embolism. Treatment should be surgical excision on cardiopulmonary bypass, a procedure performed safely with excellent outcome.
Key Words: Ascending aorta; Embolism; Thrombosis; Cardiopulmonary bypass</description><identifier>ISSN: 1569-9293</identifier><identifier>EISSN: 1569-9285</identifier><identifier>DOI: 10.1510/icvts.2009.206268</identifier><identifier>PMID: 19454418</identifier><language>eng</language><publisher>England: Eur Assoc Cardio Surg</publisher><subject>Acute Disease ; Administration, Oral ; Anticoagulants - administration & dosage ; Aortic Diseases - complications ; Aortic Diseases - diagnosis ; Aortic Diseases - therapy ; Aortography - methods ; Blood Vessel Prosthesis Implantation ; Cardiopulmonary Bypass ; Circulatory Arrest, Deep Hypothermia Induced ; Embolism - diagnosis ; Embolism - etiology ; Embolism - therapy ; Female ; Humans ; Ischemia - diagnosis ; Ischemia - etiology ; Ischemia - therapy ; Ischemic Attack, Transient - etiology ; Magnetic Resonance Angiography ; Middle Aged ; Sternum - surgery ; Thrombosis - complications ; Thrombosis - diagnosis ; Thrombosis - therapy ; Tomography, X-Ray Computed ; Treatment Failure ; Upper Extremity - blood supply</subject><ispartof>Interactive cardiovascular and thoracic surgery, 2009-09, Vol.9 (3), p.532-534</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2888-3c003e9072937a5fb671f81f1b99dc42d0646891e65e06fc3291c79c0de9280b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27933,27934</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19454418$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pousios, Dimitrios</creatorcontrib><creatorcontrib>Velissaris, Theodoros</creatorcontrib><creatorcontrib>Duggan, Simon</creatorcontrib><creatorcontrib>Tsang, Geoff</creatorcontrib><title>Floating intra-aortic thrombus presenting as distal arterial embolism</title><title>Interactive cardiovascular and thoracic surgery</title><addtitle>Interact Cardiovasc Thorac Surg</addtitle><description>Department of Cardiothoracic Surgery, Wessex Cardiac Unit, Southampton General Hospital, Southampton, UK
*Corresponding author. 105 Captains Place, Southampton SO14 3TF, Hampshire, UK. Tel.: +447970539749. E-mail address : dpousios{at}yahoo.com (D. Pousios).
Floating thrombi in the aorta are a rare finding in the absence of any coagulation abnormality. They often represent a surgical emergency. Our case refers to a 45-year-old woman who presented with acute ischemia of the upper extremity. This was a result of peripheral embolism originating in a floating thrombus in the ascending aorta. A free-floating lesion held by a pedicle from the lateral ascending aortic wall was demonstrated using computed tomography and magnetic resonance scans. There was no pre-existing clotting abnormality. Conservative treatment with oral anticoagulation was not successful in removing the lesion. Therefore, a surgical approach was selected through a median sternotomy and cardiopulmonary bypass. Under temporary hypothermic circulatory arrest, the ascending aorta was opened. The lesion was removed along with a rim of aortic wall, circulation was re-established and the aorta was reconnected with use of a synthetic interposition graft. Postoperative course was uneventful. The patient was discharged on oral anticoagulation. Histopathology confirmed the lesion as thrombus. Only a few cases of intra-aortic thrombus without any coagulation abnormality basis are described in literature. Occasionally, they present as distal embolism. Treatment should be surgical excision on cardiopulmonary bypass, a procedure performed safely with excellent outcome.
Key Words: Ascending aorta; Embolism; Thrombosis; Cardiopulmonary bypass</description><subject>Acute Disease</subject><subject>Administration, Oral</subject><subject>Anticoagulants - administration & dosage</subject><subject>Aortic Diseases - complications</subject><subject>Aortic Diseases - diagnosis</subject><subject>Aortic Diseases - therapy</subject><subject>Aortography - methods</subject><subject>Blood Vessel Prosthesis Implantation</subject><subject>Cardiopulmonary Bypass</subject><subject>Circulatory Arrest, Deep Hypothermia Induced</subject><subject>Embolism - diagnosis</subject><subject>Embolism - etiology</subject><subject>Embolism - therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Ischemia - diagnosis</subject><subject>Ischemia - etiology</subject><subject>Ischemia - therapy</subject><subject>Ischemic Attack, Transient - etiology</subject><subject>Magnetic Resonance Angiography</subject><subject>Middle Aged</subject><subject>Sternum - surgery</subject><subject>Thrombosis - complications</subject><subject>Thrombosis - diagnosis</subject><subject>Thrombosis - therapy</subject><subject>Tomography, X-Ray Computed</subject><subject>Treatment Failure</subject><subject>Upper Extremity - blood supply</subject><issn>1569-9293</issn><issn>1569-9285</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkDFPwzAQhS0EoqXwA1hQJraUsx079ogqCkiVWGC2HMdpjZym2A6If0_aVHS5u-G9d3cfQrcY5phheHDmO8U5AZBD4YSLMzTFjMtcEsHO_2dJJ-gqxk8ALIHCJZpgWbCiwGKKnpa-08lt15nbpqBz3YXkTJY2oWurPma7YKPdHgQ6ZrWLSftMh2SDGwbbVp13sb1GF4320d4c-wx9LJ_eFy_56u35dfG4yg0RQuTUAFAroRxOKjVrKl7iRuAGV1LWpiA18IILiS1nFnhjKJHYlNJAbYePoKIzdD_m7kL31duYVOuisd7rre36qHjJBGG4HIR4FJrQxRhso3bBtTr8Kgxqz04d2Kk9OzWyGzx3x_C-am19chxhnbZv3Hrz44JVsdXeD3IyxklFFaOE_gHVNnjM</recordid><startdate>20090901</startdate><enddate>20090901</enddate><creator>Pousios, Dimitrios</creator><creator>Velissaris, Theodoros</creator><creator>Duggan, Simon</creator><creator>Tsang, Geoff</creator><general>Eur Assoc Cardio Surg</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20090901</creationdate><title>Floating intra-aortic thrombus presenting as distal arterial embolism</title><author>Pousios, Dimitrios ; Velissaris, Theodoros ; Duggan, Simon ; Tsang, Geoff</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2888-3c003e9072937a5fb671f81f1b99dc42d0646891e65e06fc3291c79c0de9280b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Acute Disease</topic><topic>Administration, Oral</topic><topic>Anticoagulants - administration & dosage</topic><topic>Aortic Diseases - complications</topic><topic>Aortic Diseases - diagnosis</topic><topic>Aortic Diseases - therapy</topic><topic>Aortography - methods</topic><topic>Blood Vessel Prosthesis Implantation</topic><topic>Cardiopulmonary Bypass</topic><topic>Circulatory Arrest, Deep Hypothermia Induced</topic><topic>Embolism - diagnosis</topic><topic>Embolism - etiology</topic><topic>Embolism - therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Ischemia - diagnosis</topic><topic>Ischemia - etiology</topic><topic>Ischemia - therapy</topic><topic>Ischemic Attack, Transient - etiology</topic><topic>Magnetic Resonance Angiography</topic><topic>Middle Aged</topic><topic>Sternum - surgery</topic><topic>Thrombosis - complications</topic><topic>Thrombosis - diagnosis</topic><topic>Thrombosis - therapy</topic><topic>Tomography, X-Ray Computed</topic><topic>Treatment Failure</topic><topic>Upper Extremity - blood supply</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pousios, Dimitrios</creatorcontrib><creatorcontrib>Velissaris, Theodoros</creatorcontrib><creatorcontrib>Duggan, Simon</creatorcontrib><creatorcontrib>Tsang, Geoff</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Interactive cardiovascular and thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pousios, Dimitrios</au><au>Velissaris, Theodoros</au><au>Duggan, Simon</au><au>Tsang, Geoff</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Floating intra-aortic thrombus presenting as distal arterial embolism</atitle><jtitle>Interactive cardiovascular and thoracic surgery</jtitle><addtitle>Interact Cardiovasc Thorac Surg</addtitle><date>2009-09-01</date><risdate>2009</risdate><volume>9</volume><issue>3</issue><spage>532</spage><epage>534</epage><pages>532-534</pages><issn>1569-9293</issn><eissn>1569-9285</eissn><abstract>Department of Cardiothoracic Surgery, Wessex Cardiac Unit, Southampton General Hospital, Southampton, UK
*Corresponding author. 105 Captains Place, Southampton SO14 3TF, Hampshire, UK. Tel.: +447970539749. E-mail address : dpousios{at}yahoo.com (D. Pousios).
Floating thrombi in the aorta are a rare finding in the absence of any coagulation abnormality. They often represent a surgical emergency. Our case refers to a 45-year-old woman who presented with acute ischemia of the upper extremity. This was a result of peripheral embolism originating in a floating thrombus in the ascending aorta. A free-floating lesion held by a pedicle from the lateral ascending aortic wall was demonstrated using computed tomography and magnetic resonance scans. There was no pre-existing clotting abnormality. Conservative treatment with oral anticoagulation was not successful in removing the lesion. Therefore, a surgical approach was selected through a median sternotomy and cardiopulmonary bypass. Under temporary hypothermic circulatory arrest, the ascending aorta was opened. The lesion was removed along with a rim of aortic wall, circulation was re-established and the aorta was reconnected with use of a synthetic interposition graft. Postoperative course was uneventful. The patient was discharged on oral anticoagulation. Histopathology confirmed the lesion as thrombus. Only a few cases of intra-aortic thrombus without any coagulation abnormality basis are described in literature. Occasionally, they present as distal embolism. Treatment should be surgical excision on cardiopulmonary bypass, a procedure performed safely with excellent outcome.
Key Words: Ascending aorta; Embolism; Thrombosis; Cardiopulmonary bypass</abstract><cop>England</cop><pub>Eur Assoc Cardio Surg</pub><pmid>19454418</pmid><doi>10.1510/icvts.2009.206268</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Acute Disease Administration, Oral Anticoagulants - administration & dosage Aortic Diseases - complications Aortic Diseases - diagnosis Aortic Diseases - therapy Aortography - methods Blood Vessel Prosthesis Implantation Cardiopulmonary Bypass Circulatory Arrest, Deep Hypothermia Induced Embolism - diagnosis Embolism - etiology Embolism - therapy Female Humans Ischemia - diagnosis Ischemia - etiology Ischemia - therapy Ischemic Attack, Transient - etiology Magnetic Resonance Angiography Middle Aged Sternum - surgery Thrombosis - complications Thrombosis - diagnosis Thrombosis - therapy Tomography, X-Ray Computed Treatment Failure Upper Extremity - blood supply |
title | Floating intra-aortic thrombus presenting as distal arterial embolism |
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